In-Home Therapy for Prostate Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether receiving prostate cancer treatment at home is as safe and satisfying as receiving it in a clinic. It specifically targets Black men whose prostate cancer has spread or returned after treatment. The goal is to determine if home treatment can ease life by reducing stress and increasing comfort while maintaining effectiveness. Men currently receiving or planning to start certain prostate cancer treatments, such as Cancer Connected Access and Remote Expertise (CARE) Beyond Walls (CCBW), and who can receive care from a home health nurse, might be suitable candidates. As a Phase 2 trial, the research focuses on measuring the treatment's effectiveness in an initial, smaller group of participants.
Do I need to stop my current medications to join the trial?
The trial does not specify if you need to stop your current medications. However, you must be on or plan to start one of the eligible cancer treatment regimens, and you should continue your current treatment for at least 18 to 24 weeks, depending on the regimen.
What prior data suggests that this method is safe for in-home cancer therapy?
Research has shown that receiving cancer treatment at home is safe and well-tolerated. Early results from studies on Cancer Connected Access and Remote Expertise (CCBW) have not identified any safety issues. More than 140 chemotherapy treatments have been administered at home without problems. These findings suggest that home cancer treatment can be as safe as treatment in a clinic.12345
Why are researchers excited about this trial?
Unlike the standard of care for prostate cancer, which typically involves treatments like surgery, radiation, or hormone therapy administered in a clinical setting, the Cancer Connected Access and Remote Expertise (CARE) Beyond Walls (CCBW) approach offers a unique in-home therapy option. This treatment is distinctive because it combines initial clinic-based care with subsequent at-home treatment, allowing patients to continue their therapy in the comfort of their homes. This method not only maintains the effectiveness of standard care but also enhances convenience and accessibility, potentially improving patient compliance and quality of life. Researchers are excited about this approach as it could revolutionize how cancer care is delivered, particularly for those who face challenges accessing traditional healthcare facilities.
What evidence suggests that in-home cancer therapy using CARE Beyond Walls is effective for prostate cancer?
Research has shown that receiving cancer care at home, such as through the Cancer Connected Access and Remote Expertise (CARE) Beyond Walls (CCBW) program, is safe and feasible. In this trial, participants will first receive standard care in the clinic for 6-12 weeks, then transition to home treatment with CCBW for 12-24 weeks, provided there is no disease progression or unacceptable toxicity. Studies have found that nearly 75% of patients prefer home treatment over clinic visits, indicating greater satisfaction with home care. The Mayo Clinic found that home-based care can reduce stress and financial costs. These findings support the idea that home cancer therapy might enhance overall patient well-being and improve adherence to treatment plans.13678
Who Is on the Research Team?
Roxana S. Dronca, MD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
This trial is for Black men with prostate cancer that's either locally advanced, has returned after treatment (biochemically recurrent), or has spread to other parts of the body (metastatic). It aims to see if receiving therapy at home offers benefits over in-clinic care.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
In-clinic Treatment
Participants receive standard of care treatment in the clinic
At-home Treatment
Participants receive treatment in the home with CCBW in the absence of disease progression or unacceptable toxicity
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cancer Connected Access and Remote Expertise (CARE) Beyond Walls (CCBW)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor