Abiprubart for Sjögren's Syndrome
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you must stop all current medications, but you cannot change medications for dry mouth/eyes within 30 days before the trial or during it. Injectable corticosteroids must be stopped 8 weeks before joining.
How is the drug Abiprubart different from other treatments for Sjögren's syndrome?
What is the purpose of this trial?
Primary objective of the study is to evaluate the effect of abiprubart on an established systemic disease activity measure for Sjögren's Disease.
Eligibility Criteria
This trial is for individuals with Sjögren's Disease, a condition where the immune system attacks glands that make tears and saliva. The eligibility criteria are not fully listed here, but typically include having a diagnosis of Sjögren's Syndrome and meeting certain health standards.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Randomized Double-blind Treatment
Participants receive either abiprubart or placebo in a double-blind manner for 24 weeks
Active Treatment
Participants receive active abiprubart treatment for an additional 24 weeks
Safety Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Abiprubart
Find a Clinic Near You
Who Is Running the Clinical Trial?
Kiniksa Pharmaceuticals International, plc
Lead Sponsor
Kiniksa Pharmaceuticals, GmbH
Industry Sponsor