Your session is about to expire
← Back to Search
Stem Cell Therapy for Dry Mouth After Cancer Treatment
Study Summary
This trial will study if it is safe to use a person's own stem cells to help treat dry mouth after radiation therapy for head and neck cancer. Up to 12 people will be enrolled and the study will last up to 2 years.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I believe my saliva production is less than 80% of what it was before radiation.I haven't had cancer in the past 2 years, except for certain low-risk or treated early-stage cancers.I have confirmed I am not pregnant and will use birth control during and after the study.I am between 18 and 90 years old.The researchers have decided that you are not suitable to participate in the study for other reasons.I have an autoimmune disease like Sjögren's, lupus, or type I diabetes.You are allergic to lidocaine.I have one submandibular gland.I have untreated yeast infection in my mouth.I have had salivary gland stones in the past.I had head and neck cancer, finished treatment over 2 years ago, and currently show no signs of the disease.I can care for myself but may not be able to do active work.I am not pregnant, breastfeeding, or planning to become pregnant during the study.I am willing and able to follow all study rules and attend all appointments.I am not taking any anti-cholinergic medications.I have chronic graft versus host disease.
- Group 1: Treatment with MSCs
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is participation in this research limited to individuals of a certain age?
"To meet the requirements of this study, participants must be between 18 to 90 years in age. For younger patients, there are eighteen prospective trials while those over 65 can choose from 445 different studies."
Is this a pioneering research effort?
"Since 2011, Autologous bone-marrow derived interferon gamma stimulated mesenchymal stromal cells has been under investigation. BioMérieux was the original sponsor of this research, and following a successful Phase 1 trial involving 20 patients, it quickly received approval for its official Phase 3 drug study. Currently there are 37 clinical trials in 19 different countries with 23 cities hosting these studies."
Has the FDA sanctioned Autologous bone-marrow derived, interferon gamma stimulated mesenchymal stromal cells for commercial use?
"Autologous bone-marrow derived, interferon gamma stimulated mesenchymal stromal cells demonstrate low degree of safety according to our scale rating system; a score of 1 is attributed due to the limited amount of research available on their efficacy."
What is the participation rate of this investigation?
"This research project is no longer accepting enrollees. It was first published on February 18th 2022, and the most recent update to its status occurred November 21st of that same year. For those looking for alternative studies in xerostomia, 413 trials are presently welcoming patients; 37 clinical trails also exist involving Autologous bone-marrow derived interferon gamma activated mesenchymal stromal cells actively searching for participants."
Are there still open slots for this trial's participants?
"Per the clinicaltrials.gov website, this trial is not seeking participants at present. It was initially launched on February 18th 2022 and last revised on November 21st 2022. Despite that, there are currently 450 different studies actively recruiting patients for their trials."
What criteria must be met in order to qualify for this experiment?
"This medical trial is seeking a minimum of 6 patients with xerostomia and between the ages of 18-90."
Share this study with friends
Copy Link
Messenger