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Spironolactone 100mg for Non-alcoholic Fatty Liver Disease
Study Summary
This trial is looking at whether androgens, or "male sex hormones" play a role in NASH in women. NASH is a fat-related liver inflammation and scarring that is projected to be the leading cause of cirrhosis in the United States. Spironolactone, an androgen blocking medication, will be used to see if it has an effect on NASH. The study is primarily focused on feasibility, but will also explore how blocking testosterone receptors might alter the biologic processes that promote NASH in women.
- Non-alcoholic Fatty Liver Disease (NAFLD)
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Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 2 & 3 trial • 20 Patients • NCT02585843Trial Design
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Frequently Asked Questions
What qualifications must prospective participants meet to take part in this experiment?
"To be deemed eligible for this trial, candidates must have been diagnosed with nonalcoholic steatohepatitis and fall between the ages of 18-45. The team is looking to recruit a total of 30 participants."
Does this medical trial take into consideration participants aged under thirty?
"The study is seeking participants who are within the ages of 18 and 45."
Are there still opportunities to join this experiment?
"Indeed, clinicaltrials.gov reveals that the trial is currently enrolling participants and was originally listed on January 9th 2019. As of September 9 2022, 30 people from a single medical centre are needed for participation."
What is the total size of the patient cohort in this research endeavor?
"Affirmative. Clinicaltrials.gov data confirms that this clinical trial, which was initially posted on January 9th 2019, is actively seeking participants. 30 patients need to be enrolled at a single medical centre for the study's completion."
Has Spironolactone 100mg been the focus of prior research endeavors?
"At this time, 28 medical trials are in progress that explore the effects of Spironolactone 100mg. Of those studies, 7 are at Phase 3 and 293 different sites across the world have begun to experiment with this medication. The majority of these experiments take place in Boston, Massachusetts."
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