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LY3857210 for Chronic Pain

Phase 2
Waitlist Available
Research Sponsored by Eli Lilly and Company
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, up to week 8
Awards & highlights

Study Summary

This trial tests a drug to help relieve nerve pain caused by diabetes.

Eligible Conditions
  • Chronic Pain
  • Diabetic Neuropathy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, up to week 8
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, up to week 8 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from Baseline in Average Pain Intensity as Measured by the Numeric Rating Scale (NRS)
Secondary outcome measures
Change from Baseline for Overall Improvement as Measured by Patient's Global Impression of Change
Pain
Change from Baseline in the Brief Pain Inventory-Short Form (BPI-SF) Total Interference Score
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: LY3857210Experimental Treatment1 Intervention
Participants will be given LY3857210 orally.
Group II: PlaceboPlacebo Group1 Intervention
Participants will be given placebo orally.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
LY3857210
2022
Completed Phase 2
~430

Find a Location

Who is running the clinical trial?

Eli Lilly and CompanyLead Sponsor
2,605 Previous Clinical Trials
3,199,539 Total Patients Enrolled
4 Trials studying Chronic Pain
10,714 Patients Enrolled for Chronic Pain
Study DirectorEli Lilly and Company
1,338 Previous Clinical Trials
403,714 Total Patients Enrolled
3 Trials studying Chronic Pain
10,307 Patients Enrolled for Chronic Pain

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Did the FDA sign off on LY3852710?

"LY3852710's safety is supported by some data, but since this is only a phase 2 trial and there is no evidence for efficacy, it was given a score of 2."

Answered by AI

Can people with the condition still sign up for the research project?

"This particular clinical trial is not currently looking for patients, as per the information available on clinicaltrials.gov. This study was first posted on November 14th, 2022 and last updated eleven days ago. There are 717 other trials searching for participants at this time."

Answered by AI

In how many different locations is this trial taking place?

"There are 28 clinical trial sites for this medication, with notable locations being Synexus Clinical Research US, Inc. in San Antonio, Texas and Northwest Clinical Research Center in Bellevue, Washington."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
Nevada
California
Other
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
What site did they apply to?
Artemis Institute for Clinical Research
CMR of Greater New Haven
Suncoast Research Group
Other
How many prior treatments have patients received?
1
2
3+
0

What questions have other patients asked about this trial?

Does the trial use placebo?
PatientReceived 1 prior treatment

Why did patients apply to this trial?

La falta de dinero. I'm here for the money. Soy Diabetica desde mis 17 anos.
PatientReceived 2+ prior treatments
I'm in a seemingly endless downward spiral with less and less hope for my existence.
PatientReceived 1 prior treatment
Tried off the shelf drugs and one prescribed drug with limited and temporary relief. The pain is chronic and disrupts my life.
PatientReceived 2+ prior treatments
~56 spots leftby Mar 2025