Ultralow Dose PET Imaging for Parkinson's Disease and Brain Tumors

No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for Parkinsonian syndromes, neuroendocrine tumors, and gliomas detection and monitoring. The main question it aims to answer is:

Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard? Participants will be injected with a radioactive tracer called 18F-FDOPA and be imaged on a new type of high sensitivity PET scanner for up to 3 hours.

Are You a Good Fit for This Trial?

Inclusion Criteria

2. ability to provide informed consent and comply with study procedures.
* must not be pregnant or breastfeeding.
I am 18 years old or older.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging

Participants are injected with a very small amount of radiotracer and imaged on a PET scanner for up to 3 hours to evaluate image quality and optimize timing and reconstruction.

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after imaging, with data aggregated annually for up to 5 years.

5 years

What Are the Treatments Tested in This Trial?

Interventions

  • 18F-FDOPA

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: ultralow dose 18F-FDOPA imaging groupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Akiva Mintz

Lead Sponsor

Trials
1
Recruited
40+