AMDX-2011P for Glaucoma
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this research study is to assess the ability of AMDX- 2011P to identify amyloid deposits in the retina of participants with Primary Open Angle Glaucoma (POAG).
Do I have to stop taking my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What safety data is available for AMDX-2011P in treating glaucoma?
The safety data for AMDX-2011P, also known as omidenepag isopropyl, includes several studies. A 3-month study in Japanese patients with open-angle glaucoma evaluated its adverse reactions. A Phase 3 study assessed its safety in patients with primary open-angle glaucoma or ocular hypertension who did not respond well to latanoprost. Phase 2 studies demonstrated its tolerability in patients with primary open-angle glaucoma and ocular hypertension, identifying 0.002% as the optimal dose. The RENGE study assessed its long-term safety over 12 months in patients with open-angle glaucoma or ocular hypertension.12345
Is AMDX-2011P a promising treatment for Glaucoma?
What data supports the idea that AMDX-2011P for Glaucoma is an effective treatment?
The available research does not provide any specific data on the effectiveness of AMDX-2011P for Glaucoma. Instead, it focuses on other treatments like the XEN45 implant and Aurolab aqueous drainage implant. Without direct data on AMDX-2011P, we cannot conclude its effectiveness for Glaucoma based on the provided information.1112131415
Who Is on the Research Team?
David Bingaman
Principal Investigator
Amydis Inc.
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single IV bolus injection of AMDX-2011P followed by safety assessments, retinal imaging, and blood collection for PK analysis
Follow-up
Participants are monitored for safety and effectiveness after treatment, including adverse events and retinal imaging
What Are the Treatments Tested in This Trial?
Interventions
- AMDX-2011P
Find a Clinic Near You
Who Is Running the Clinical Trial?
Amydis Inc.
Lead Sponsor