Study Summary
This trial will test whether a combination of two drugs is an effective treatment for endometrial cancer or endometrial carcinosarcoma.
- Endometrial Carcinosarcoma
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: 2 years
Trial Safety
Safety Progress
Side Effects for
Trial Design
1 Treatment Group
Pembrolizumab with Olaparib
1 of 1
Experimental Treatment
25 Total Participants · 1 Treatment Group
Primary Treatment: Pembrolizumab · No Placebo Group · Phase 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · Female Participants · 14 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Are there any unfilled slots for participants in this trial?
"Verified. According to clinicaltrials.gov, this medical study has initiated recruitment and is searching for 25 participants at 7 locations. It was posted on January 27th 2022 and its last update occurred on October 21st 2022." - Anonymous Online Contributor
What medical conditions have been found to be ameliorated by Pembrolizumab?
"Pembrolizumab is the go-to therapy for those with unresectable melanoma, as well as individuals facing a high risk of recurrence or microsatellite instability." - Anonymous Online Contributor
How many sites are engaged in this research endeavor?
"At present, 7 medical centres are contributing to this study. These sites include Middletown, Basking Ridge and Montvale as well as 4 other locations. To minimize any travel requirements, it is recommended that participants select the closest site to them for enrollment." - Anonymous Online Contributor
Is this a groundbreaking research endeavor?
"After AstraZeneca's initial research into pembrolizumab began in 2005, the drug was granted its Phase 1 approval. Nowadays, 1114 studies are underway for this medication at 3058 different locations and 66 countries." - Anonymous Online Contributor
To what extent has Pembrolizumab been tested in other scientific experiments?
"Currently, 1114 clinical trials are researching the efficacy of Pembrolizumab with 143 studies at Phase 3. Out of all the locations conducting these experiments, Houston Texas is a major hub - though there are 42751 operating sites around the world." - Anonymous Online Contributor
What is the enrollment capacity for this clinical experiment?
"Affirmative. According to clinicaltrials.gov, this trial is now open for enrollment and was initially published on January 27th 2022 with the most recent update occurring October 21st of that same year. 25 study participants are needed between 7 distinct medical centres." - Anonymous Online Contributor
What potential adverse reactions might one experience while using Pembrolizumab?
"The safety of pembrolizumab is estimated to be a 2, taking into account the findings of this Phase 2 trial. Although data confirming its efficacy has yet to emerge, there are studies that support its relative safeness." - Anonymous Online Contributor