TNX-601 ER for Depression
(UPLIFT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a medication called TNX-601 ER to see if it can help people with depression by improving their mood through changes in brain chemicals.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
How is the drug TNX-601 ER different from other depression treatments?
TNX-601 ER is unique because it may involve a mechanism similar to traxoprodil, which targets specific brain pathways (BDNF/ERK/CREB and AKT/FOXO/Bim) for rapid and long-lasting antidepressant effects. This approach is different from traditional antidepressants, which often take longer to show effects.12345
Who Is on the Research Team?
Gregory Sullivan, MD
Principal Investigator
Tonix Pharmaceuticals
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either TNX-601 ER or placebo for 6 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Placebo
- TNX-601 ER
Find a Clinic Near You
Who Is Running the Clinical Trial?
Tonix Pharmaceuticals, Inc.
Lead Sponsor
Rho, Inc.
Industry Sponsor