High Dose Quadrivalent Inactivated Influenza Vaccine for Communicable Diseases
High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients
See full descriptionAbout the trial for Communicable Diseases
Treatment Groups
This trial involves 2 different treatments. High Dose Quadrivalent Inactivated Influenza Vaccine is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
Eligibility
This trial is for patients born any sex of any age. There are 5 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether High Dose Quadrivalent Inactivated Influenza Vaccine will improve 2 primary outcomes and 2 secondary outcomes in patients with Communicable Diseases. Measurement will happen over the course of Within 7 days post-vaccination.
Who is running the study
Principal InvestigatorPatient Q & A Section
Can communicable diseases be cured?
A combination of a focus on prevention and public education, as well as the development of improved diagnostic tools, could help to manage and treat communicable diseases.
What are the signs of communicable diseases?
Fever, cough with or without dyspnoea, fever above 39 degrees C and fatigue with a low white blood cell count are all very suggestive of a communicable disease such as viral pneumonia.
What causes communicable diseases?
Some of these factors appeared to have the greatest impact on the risk of acquiring a noncommunicable disease. It can also be noted that only about half of the risk factors had a significant impact on developing both types of disease. The most important contribution to acquiring a noncommunicable disease was high blood pressure.
What is communicable diseases?
Communicable diseases are diseases spread by a pathogen from one person to another via direct contact or airways. They include respiratory infections. Some of the common diseases are small, short-term infections such as sore throat.\n
What are common treatments for communicable diseases?
Communicable diseases commonly treated include, antibiotics for bacterial infections, hepatitis B vaccinations, vaccination for influenza, measles, chicken pox, and other viral infections. Other treatment options include preventive measures such as pap smears and vaccination.\n\nA significant prevalence of people in the community are treated by the general practitioners for a wide range of ailments, many without even being diagnosed with a disease and with many of the treatments involving undesirable side effects. A substantial group of the patients are either given no treatment at all, or prescribed medication. The overwhelming majority of patients are treated with prescription medication while the patients of the general practitioners are treated with over the counter medication.
How many people get communicable diseases a year in the United States?
Each year, approximately 26 million Americans encounter one or more illnesses brought on by one or more opportunistic pathogens. Communicable diseases represent a leading cause of death in US adults, accounting annually for around 12% of all non-sudden death.
Has high dose quadrivalent inactivated influenza vaccine proven to be more effective than a placebo?
Results from three clinical trials support a benefit in risk of serious complications following vaccination with the quadrivalent inactivated influenza vaccine compared with a placebo. Vaccinating health care workers substantially reduces morbidity from influenza infections.
Does communicable diseases run in families?
Findings from a recent study provides epidemiological evidence that Sudden infant death is closely related to infectious diseases and poor hygiene. The high prevalence of many pathogens and the relationship between exposure to microbes and sudden infant death warrants further investigation of factors contributing to early death from pathogens.
Does high dose quadrivalent inactivated influenza vaccine improve quality of life for those with communicable diseases?
There were no differences in [QOL] change between patients with CAD and those without CAD, but higher doses of IDOIV were associated with higher QOL improvements. These data support the hypothesis that IDOIV might be useful for reducing [QOL] changes in a subgroup of patients with CAD. Future studies seem warranted in larger samples with greater statistical power and including other aspects of [QOL] improvement.
Is high dose quadrivalent inactivated influenza vaccine safe for people?
quadrivalent quad-T of inactivated H1N1 influenza vaccine was well tolerated in adults at a dose of 500-650 µg and showed comparable immunogenicity to a standard dose of inactivated H1N1 influenza vaccine.
Who should consider clinical trials for communicable diseases?
Despite the large number of trials involving patients with chronic conditions, few trials focused on patients with communicable diseases. When considering this important unmet need, the results of RCTs should be considered with caution, and the limitations of single-center (and probably biased) studies should be considered before adopting them as evidence base for clinical treatment in the absence of evidence from network meta-analyses and other well-designed trials.
What is the average age someone gets communicable diseases?
There is no consensus on the timing, duration or frequency of health interventions aiming at preventing communicable diseases; most of these interventions are aimed at children and teenagers. For adults, it is recommended that age-appropriate screening and treatment of adults who are sexually active should be an important priority for individualized preventive programs that target high-risk groups.