EVO756 for Chronic Urticaria
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will evaluate the efficacy and safety of different doses of EVO756 in adults with moderate to severe chronic spontaneous urticaria (CSU).
Will I have to stop taking my current medications?
If you are taking H1-antihistamines, you must continue on a stable regimen for at least 4 weeks before starting the trial and throughout the study. The protocol does not specify about other medications, so it's best to discuss with the trial team.
Is EVO756 safe for humans?
How does the drug EVO756 differ from other treatments for chronic urticaria?
EVO756 is unique because it may offer a novel approach to treating chronic urticaria, potentially targeting the autoimmune aspect of the condition, unlike traditional antihistamines or corticosteroids that primarily address symptoms. This could make it particularly beneficial for patients who do not respond well to existing therapies.36789
What evidence supports the effectiveness of the drug EVO756 for chronic urticaria?
The research highlights the effectiveness of omalizumab, a biologic drug, in improving disease control and quality of life for patients with chronic urticaria. While EVO756 is not directly mentioned, the success of similar biologic treatments like omalizumab suggests potential effectiveness for EVO756 in treating chronic urticaria.136710
Are You a Good Fit for This Trial?
Adults with moderate to severe chronic spontaneous urticaria (CSU) who haven't responded well to antihistamines can join. They must have a Urticaria Activity Score of 16 or more and been diagnosed for at least 3 months. Participants should not have other diseases causing similar symptoms, significant health issues unrelated to CSU, or be on certain medications.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive different doses of EVO756 or placebo to evaluate efficacy and safety
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- EVO756
Find a Clinic Near You
Who Is Running the Clinical Trial?
Evommune, Inc.
Lead Sponsor