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Mindfulness Training for Cancer Pain

Phase 2

Recruiting

Led By Jun Mao, MD, MSCE

Research Sponsored by Memorial Sloan Kettering Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Having had pain for at least 3 months and at least 15 days with pain in the preceding 30 days

Having a pain (musculoskeletal, generalized, or neuropathic) rating of 4 or greater in worst pain on a 0-10 numerical rating scale in the preceding week

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

Study Summary

This trial aims to see if mindfulness-based interventions, like Mindfulness-oriented Recovery Enhancement, can help reduce chronic pain in cancer patients. #mindfulness #meditation #cancer #pain

Who is the study for?

This trial is for English-speaking adults (18+) with a history of any type of cancer, who are either in remission or have stable disease. Participants must be experiencing chronic pain related to cancer, rating their worst pain at 4 or higher on a scale up to 10, and have had this pain for over 3 months. They should be able to attend video calls in a private setting and commit to the study procedures.Check my eligibility

What is being tested?

The trial is testing Mindfulness-oriented Recovery Enhancement (MORE), which uses mindfulness meditation practices aimed at reducing chronic cancer-related pain. Participants will either receive MORE treatments or follow standard care for managing their pain, and they'll be randomly assigned to one of these two groups.See study design

What are the potential side effects?

Mindfulness-based interventions like MORE typically do not involve medication; therefore, physical side effects are minimal. However, participants may experience emotional discomfort as they become more aware of thoughts and sensations during mindfulness practice.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have experienced pain for at least 3 months, with pain on at least 15 days in the last month.

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My worst pain level in the last week was 4 or higher on a scale of 0 to 10.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Rate of participant enrollment to the study

Trial Design

4Treatment groups

Experimental Treatment

Placebo Group

Group I: 8-hour MORE treatmentsExperimental Treatment1 Intervention

Patients in the 8-hour MORE format will receive one 2hrs treatment a week for 4 consecutive weeks (as per study schema: from week 1 to week 4).

Group II: 2-hour MORE treatmentsExperimental Treatment1 Intervention

Patients in the 2-hour MORE format will receive one 2hrs treatment (as per study schema: in week 1).

Group III: 16-hour MORE treatmentsExperimental Treatment1 Intervention

Patients in the 16-hour MORE format will receive one 2hrs treatment a week for 8 consecutive weeks (as per study schema: from week 1 to week 8).

Group IV: Wait List Control (WLC) Usual Care ProcedurePlacebo Group1 Intervention

Participants in the WLC group continue to receive their standard medical care and pain management as prescribed by their physicians or other health care providers.

0 / 2Eligibility criteria met

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Who is running the clinical trial?

Memorial Sloan Kettering Cancer CenterLead Sponsor

1,936 Previous Clinical Trials

588,822 Total Patients Enrolled

2 Trials studying Chronic Pain

370 Patients Enrolled for Chronic Pain

Jun Mao, MD, MSCEPrincipal InvestigatorMemorial Sloan Kettering Cancer Center

9 Previous Clinical Trials

1,954 Total Patients Enrolled

1 Trials studying Chronic Pain

360 Patients Enrolled for Chronic Pain

Media Library

Mindfulness-oriented Recovery Enhancement (MORE) Clinical Trial Eligibility Overview. Trial Name: NCT05877521 — Phase 2

Chronic Pain Research Study Groups: Wait List Control (WLC) Usual Care Procedure, 16-hour MORE treatments, 8-hour MORE treatments, 2-hour MORE treatments

Chronic Pain Clinical Trial 2023: Mindfulness-oriented Recovery Enhancement (MORE) Highlights & Side Effects. Trial Name: NCT05877521 — Phase 2

Mindfulness-oriented Recovery Enhancement (MORE) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05877521 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has the FDA sanctioned sixteen hours or more treatments for this therapy?

"With no clinical evidence of efficacy, the 16-hour MORE treatment received a score of 2 on our safety scale. Nevertheless, there is some data which suggests that it may be safe to use in a Phase 2 setting."

Answered by AI

Are there openings to partake in this research endeavor?

"According to clinicaltrials.gov, this research requires the recruitment of participants and was first made available on May 16th 2023; it has since been edited as recently as May 17th 2023."

Answered by AI

How many individuals are currently participating in this medical experiment?

"Correct. According to the clinicaltrials.gov website, this research project is actively seeking participants since May 16th 2023 - with an update on 17th of same month. 60 individuals from one site are required for enrolment in the trial."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief

2023. "Mindfulness-oriented Recovery Enhancement (MORE) for Cancer Pain Relief". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05877521.

All > American Chronic Pain