Y-90 Radioembolization for Kidney Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This phase I/II trial tests the safety, side effects and effectiveness of radioembolization with yttrium-90 (Y-90) in patients with early stage renal cell carcinoma. Y-90 is a radioactive chemical that is incorporated into millions of very tiny glass spheres. These spheres are injected into the artery that feeds the cancer. This process is called radioembolization. Y-90 radioembolization may be a safe and effective treatment for patients with early stage renal cell carcinoma.
Do I need to stop my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial team or your doctor.
Is Y-90 radioembolization generally safe for humans?
How is Y-90 radioembolization treatment different for kidney cancer?
Y-90 radioembolization is unique because it delivers high-dose radiation directly to kidney tumors through tiny beads, minimizing damage to surrounding healthy tissue. This targeted approach is different from traditional treatments like surgery or systemic chemotherapy, which affect the whole body.16789
What data supports the effectiveness of the treatment Yttrium-90 Radioembolization for kidney cancer?
Yttrium-90 radioembolization has shown effectiveness in treating liver cancer and liver metastases from lung cancer, with high tumor response rates and extended patient survival. This suggests potential benefits for kidney cancer, as the treatment involves delivering targeted radiation to tumors, similar to its use in other cancers.110111213
Who Is on the Research Team?
Siddharth A Padia
Principal Investigator
UCLA / Jonsson Comprehensive Cancer Center
Are You a Good Fit for This Trial?
This trial is for patients with early stage renal cell carcinoma, a type of kidney cancer. Participants should be suitable candidates for the specific artery injection procedure used in this study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Patients undergo radioembolization with yttrium Y 90 glass microspheres (TheraSphere) given intra-arterially
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Yttrium-90 (Y90) Radioembolization
Find a Clinic Near You
Who Is Running the Clinical Trial?
Jonsson Comprehensive Cancer Center
Lead Sponsor
Boston Scientific Corporation
Industry Sponsor
Michael F. Mahoney
Boston Scientific Corporation
Chief Executive Officer since 2016
MBA from Wake Forest University, BBA in Finance from the University of Iowa
Kenneth Stein
Boston Scientific Corporation
Chief Medical Officer since 2020
MD from Harvard Medical School, MMSc in Clinical Investigation from Harvard-MIT Division of Health Sciences and Technology