BMS-986528 for Rheumatoid Arthritis

Not yet recruiting at 30 trial locations
BC
Overseen ByBMS Clinical Trials Contact Center www.BMSClinicalTrials.com
Age: 18+
Sex: Any
Trial Phase: Phase 1 & 2
Sponsor: Bristol-Myers Squibb
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the preliminary evidence of disease-modifying effect of BMS-986528 in participants with refractory, difficult-to-treat rheumatoid arthritis (RA).

Who Is on the Research Team?

BS

Bristol-Myers Squibb

Principal Investigator

Bristol-Myers Squibb

Are You a Good Fit for This Trial?

Inclusion Criteria

I am an adult with rheumatoid arthritis that is hard to control.

Exclusion Criteria

Other protocol-defined Inclusion/Exclusion criteria apply.
I have seronegative rheumatoid arthritis and may have polymyalgia rheumatica.
I developed arthritis before I turned 18.
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What Are the Treatments Tested in This Trial?

Interventions

  • BMS-986528

How Is the Trial Designed?

10

Treatment groups

Experimental Treatment

Group I: Cohort B2Experimental Treatment1 Intervention
Group II: Cohort B1Experimental Treatment1 Intervention
Group III: Cohort A8Experimental Treatment1 Intervention
Group IV: Cohort A7Experimental Treatment1 Intervention
Group V: Cohort A6Experimental Treatment1 Intervention
Group VI: Cohort A5Experimental Treatment1 Intervention
Group VII: Cohort A4Experimental Treatment1 Intervention
Group VIII: Cohort A3Experimental Treatment1 Intervention
Group IX: Cohort A2Experimental Treatment1 Intervention
Group X: Cohort A1Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Bristol-Myers Squibb

Lead Sponsor

Trials
2,731
Recruited
4,127,000+
Headquarters
New York City, USA
Known For
Oncology & Cardiovascular
Top Products
Eliquis, Opdivo, Revlimid, Orencia
Christopher Boerner profile image

Christopher Boerner

Bristol-Myers Squibb

Chief Executive Officer since 2023

PhD in Business Administration from the Haas School of Business, University of California, Berkeley; BA in Economics and History from Washington University in St. Louis

Deepak L. Bhatt profile image

Deepak L. Bhatt

Bristol-Myers Squibb

Chief Medical Officer since 2024

MD from Yale University; MSc in Clinical Epidemiology from the University of Pennsylvania