Inhaled Isopropyl Alcohol for Children, Only

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Oishei Children's Hospital, Buffalo, NY
Children, Only+2 More
Inhaled Isopropyl Alcohol - Other
Eligibility
< 18
All Sexes
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Study Summary

To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.

Eligible Conditions

  • Children, Only
  • Vomiting
  • Nausea

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

3 Primary · 4 Secondary · Reporting Duration: 30 minutes post-intervention as compared to baseline

10 minutes post-interventnon as compared to baseline
Change in Nausea Score at 10 Minutes
30 minutes post-intervention as compared to baseline
Change in Nausea Score at 30 Minutes
Hour 10
Change in Nausea Score at Discharge
Hour 10
Nurse Satisfaction in Ease of Administering the Treatment
Parent/Caregiver Satisfaction
Hour 10
Length of Stay
Hour 10
Vomiting

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

3 Treatment Groups

Oral Ondansetron
1 of 3
Inhaled Isopropyl Alcohol
1 of 3
Inhaled Placebo
1 of 3
Active Control
Experimental Treatment
Non-Treatment Group

84 Total Participants · 3 Treatment Groups

Primary Treatment: Inhaled Isopropyl Alcohol · Has Placebo Group · Phase 2 & 3

Inhaled Isopropyl Alcohol
Other
Experimental Group · 1 Intervention: Inhaled Isopropyl Alcohol · Intervention Types: Other
Oral Ondansetron
Drug
ActiveComparator Group · 1 Intervention: Oral Ondansetron · Intervention Types: Drug
Inhaled Placebo
Other
PlaceboComparator Group · 1 Intervention: Inhaled Placebo · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 30 minutes post-intervention as compared to baseline

Trial Background

Alana Koehler, Pediatric Emergency Medicine Fellow
Principal Investigator
State University of New York at Buffalo
Closest Location: Oishei Children's Hospital · Buffalo, NY
2020First Recorded Clinical Trial
1 TrialsResearching Children, Only
2 CompletedClinical Trials

Eligibility Criteria

Age < 18 · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have nausea severity score ≥ 4/10.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.