Exercise and Cognitive Rehabilitation for Cancer Survivors
(ECO 2 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The objective of this study is to assess the preliminary effects of an integrated exercise and cognitive rehabilitation intervention (ECO), an exercise intervention (EXCAP), and a cognitive rehabilitation intervention (MAAT) as compared to usual care on objective cognition (Trail Making Test).
Who Is on the Research Team?
Kah Poh Loh
Principal Investigator
University of Rochester
Are You a Good Fit for This Trial?
This trial is for older cancer survivors aged 65 or above who have finished curative treatments, including those on endocrine therapies or post-stem cell transplant. Participants should be concerned about their memory or thinking abilities post-treatment, able to speak English, and physically capable of walking and exercising without medical contraindications.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive the integrated EXCAP and MAAT interventions over a 12-week period
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- ECO
- EXCAP
- MAAT
Trial Overview
The study compares the effects of three interventions: an integrated exercise and cognitive rehab program (ECO), an exercise-only intervention (EXCAP), and a cognitive rehab-only intervention (MAAT) against usual care in improving cognition as measured by the Trail Making Test.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Active Control
Memory and Attention Adaptation Training (MAAT) is an intervention based on cognitive behavioral therapy principles that integrates cognitive rehabilitation skills and provides education and training in adaptive behavioral coping skills, stress management techniques, and compensation strategies to address CRCD.
Exercise for Cancer Patients (EXCAP) is an individually tailored, low-to-moderate intensity, home-based walking and progressive resistance exercise program designed for patients with cancer delivered by an exercise physiologist. It also includes digital health applications, allowing the tracking of exercise adherence, barriers to exercise, and symptoms.
Patients will receive the integrated EXCAP and MAAT interventions.
Patients in the control group will receive care as usual.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Rochester
Lead Sponsor
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