Automated MR-Guided Radiation for Breast Cancer
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Automated Breast Radiation Therapy?
Research shows that using MRI (a type of imaging that provides detailed pictures of the inside of the body) to guide radiation therapy can improve how well the treatment targets the tumor, especially in breast cancer. This approach helps in reducing the amount of healthy tissue exposed to radiation, potentially lowering side effects.12345
Is MR-guided radiation therapy safe for humans?
Research on MR-guided radiation therapy, including for breast cancer, suggests it can reduce the amount of healthy tissue exposed to radiation, potentially lowering the risk of side effects. This approach is being studied to improve safety by making treatment more precise and minimizing damage to surrounding tissues.46789
How does Automated Breast Radiation Therapy differ from other breast cancer treatments?
Automated Breast Radiation Therapy is unique because it uses MRI-guided radiation, which provides better soft-tissue contrast and allows for real-time adaptation to changes in the tumor's position during treatment. This approach can improve the precision of radiation delivery compared to traditional methods that rely on CT scans.1231011
What is the purpose of this trial?
In the proposed research study, we are investigating the feasibility of integrating automated planning tools to MR images acquired using a novel MR-guided linac, for on-line adaptive radiation treatment. However, these on-line automation tools require further technical refinement and clinical validation. The goal of this research proposal is to develop an on-line MR-guided radiation therapy process for adapting breast IMRT treatment. Such an approach will provide early stage breast cancer patients timely access to high-quality adaptive treatments without exposure to additional ionizing radiation.
Research Team
Robert Dinniwell, M.D.
Principal Investigator
Princess Margaret Cancer Centre
Tom Purdie, Physicist
Principal Investigator
Princess Margaret Cancer Centre
Eligibility Criteria
This trial is for female patients over 18 with any stage of breast cancer, who will undergo standard whole breast radiation therapy. It's open to those who've had surgery or chemotherapy for any cancer type and can consent in writing.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants receive MR-guided radiation therapy using automated planning tools for breast IMRT treatment
Follow-up
Participants are monitored for safety and effectiveness after radiation treatment
Treatment Details
Interventions
- Automated Breast Radiation Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Health Network, Toronto
Lead Sponsor
Princess Margaret Hospital, Canada
Collaborator