Long-Term Effects Study for Childhood Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand the long-term effects of cancer and its treatments, such as radiation and chemotherapy, on individuals who survived cancer as children or young adults. Researchers will compare about 50,000 survivors with 10,000 siblings who did not have cancer to assess how treatments may affect health later in life. The trial seeks participants who survived cancers like leukemia or lymphoma before age 21 and have been cancer-free for at least five years. This study may suit those who underwent cancer treatments as children and are interested in how these treatments might impact their future health. As an unphased study, this trial offers a unique opportunity to contribute to research that could enhance future cancer care and survivorship.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to gather valuable insights into the long-term health effects and quality of life for childhood cancer survivors. This study is not about testing a new drug or treatment but about understanding the late effects of cancer and its treatment on children who have survived the disease. By identifying these impacts, researchers hope to develop better care strategies and interventions to improve the long-term well-being and life expectancy of these survivors. This trial is unique because it comprehensively looks at a broad range of outcomes, from physical health to psychological and social well-being, which are not typically addressed in standard cancer follow-ups.
Who Is on the Research Team?
Gregory T. Armstrong, MD, MSCE
Principal Investigator
St. Jude Children's Research Hospital
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Retrospective Cohort Identification
Identification and active follow-up of a cohort of approximately 50,000 cancer survivors and 10,000 sibling controls
Data Collection and Analysis
Data collection on health outcomes, treatment exposures, and familial cancer patterns; includes collection of biologic samples
Follow-up
Participants are monitored for long-term health outcomes and compared with sibling controls
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
St. Jude Children's Research Hospital
Lead Sponsor
University of Southern California
Collaborator
Children's Hospital Medical Center, Cincinnati
Collaborator
M.D. Anderson Cancer Center
Collaborator
Fred Hutchinson Cancer Center
Collaborator
University of California, San Francisco
Collaborator
Nationwide Children's Hospital
Collaborator
National Cancer Institute (NCI)
Collaborator