Peas in Chili for Blood Sugar and Appetite Control

(PEA5 Trial)

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: St. Boniface Hospital

Must not be taking: Corticosteroids, Stomach acid-lowering, Laxatives, others

Disqualifiers: Diabetes, Cardiovascular disease, Liver disease, others

Compensation: Varies

Number of Visits: 4

Duration: Approximately 4-8 weeks

24 Participants Needed

Trial Summary

What is the purpose of this trial?

This study is part of a group of studies whose overall goal is to accurately define the physiochemical and structural effects of pea varieties and relate these to blood glucose attenuation and appetite related sensations in healthy human volunteers.

Research Team

Heather Blewett, PhD

Principal Investigator

Agriculture and Agri-Food Canada

Eligibility Criteria

This trial is for generally healthy men and women aged 18-40, with a BMI of 18.5-30. They should regularly eat three meals a day and be willing to follow the study's requirements after giving informed consent.

Inclusion Criteria

Habitually consume breakfast, lunch and dinner in the morning, mid-day and evening, respectively.

Willing to provide informed consent;

Willing/able to comply with the requirements of the study.

Exclusion Criteria

Pregnant or lactating

I am unwilling or unable to eat the foods required for the study.

I have not had major surgery in the last 3 months.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants attend 4 clinic visits in a fasted state to consume chili with peas or rice and provide blood and urine samples, complete questionnaires, and have their calorie intake measured.

Approximately 4-8 weeks

4 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1-2 weeks

Treatment Details

Interventions

• Rice chili
• Split yellow pea chili
• Whole yellow pea chili

Trial Overview The study tests how different types of chili containing whole yellow peas, split yellow peas, or rice affect blood sugar levels and feelings of fullness in volunteers after they eat.

Participant Groups

Group I: Whole yellow pea Experimental Treatment 1 Intervention

Chili containing 25g available carbohydrate from whole yellow peas. Intervention: Whole yellow pea chili

Group II: Split yellow pea Experimental Treatment 1 Intervention

Chili containing 25g available carbohydrate from split yellow peas. Intervention: Split yellow pea chili

Group III: Rice-Satiety Placebo Group 1 Intervention

Rice chili with the same calories as the pea chili. Intervention: Rice chili

Group IV: Rice-PPGR Placebo Group 1 Intervention

Chili containing 25g available carbohydrate from long grain white rice. Intervention: Rice chili

Who Is Running the Clinical Trial?

St. Boniface Hospital

Lead Sponsor

Trials

55

Recruited

15,000+

Agriculture and Agri-Food Canada

Collaborator

Trials

35

Recruited

2,300+

University of Manitoba

Collaborator

Trials

628

Recruited

209,000+