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HMPL-760 for Mantle Cell Lymphoma
Study Summary
This trial is testing a new drug, HMPL-760, on patients who have already been treated for a type of cancer called CLL/SLL or NHL. They're testing how safe and tolerable the drug is, as well as its efficacy.
- Mantle Cell Lymphoma
- Follicular Lymphoma
- Chronic Lymphocytic Leukemia
- Lymphoplasmacytic Lymphoma
- Richter Syndrome
- Waldenstrom Macroglobulinemia
- Non-Hodgkin's Lymphoma
- Medial Collateral Ligament
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Has the FDA greenlit HMPL-760 for public consumption?
"HMPL-760's safety is rated 1, since this Phase 1 trial has only limited data to show efficacy and its effects on health."
Are there plentiful locations within the United States hosting this medical experiment?
"The present recruitment phase requires 12 medical sites, located in New Orleans, The Woodlands, Kansas City and other locations. To minimize the burden of travel for patients, it is recommended to select the closest centre available should you choose to participate."
Is it feasible to join this trial at the present time?
"As indicated by clinicaltrials.gov, this medical trial is in the process of recruiting participants. This investigation was initially publicized on February 15th 2022 and recently updated on November 2nd 2022."
What are the prominent goals of this medical research?
"The main metric of this trial, taken over a period between the first dose and 30 days after last dose is Adverse Event/Serious Aedverse Events Incidence. Secondary measurements include Objective Response Rate (ORR), Duration of Response (DoR) and Progression-Free Survival (PFS). ORR gauges partial or better response to therapy; DoR marks time from initial respone until progression or relapse; PFS measures survival without disease advance."
How many participants are taking part in this research project?
"To complete this clinical trial, the sponsor is looking to enrol 168 participants that meet the inclusion criteria. Several medical centres are involved, such as Tulane Cancer Center in New Orleans and Renovatio Clinical in The Woodlands."
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