ZW191 for Advanced Cancers
Trial Summary
What is the purpose of this trial?
The purpose of this study is to find out if ZW191 is safe and can treat participants with advanced cancers, including ovarian, endometrial, and non-small cell lung cancers.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you are on treatments for severe infections or have received certain cancer treatments before, it might affect your eligibility.
Research Team
Syed Raza, MD
Principal Investigator
Zymeworks BC Inc.
Eligibility Criteria
This trial is for people with advanced cancers like ovarian, endometrial, and non-small cell lung cancer. Participants must have a confirmed diagnosis of these cancers that are advanced or metastatic, measurable by certain criteria (RECIST v1.1), good heart function (LVEF ≥ 50%), and be in fairly good health overall (ECOG score of 0 or 1).Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment Part 1
Evaluation of safety and tolerability of ZW191
Treatment Part 2
Further evaluation of safety and exploration of anti-tumor activity of ZW191
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- ZW191
Find a Clinic Near You
Who Is Running the Clinical Trial?
Zymeworks BC Inc.
Lead Sponsor