Hydrate Heroes for Mental Health

Overseen By Katherine F Walters, MS

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of South Florida

Must not be taking: Benzodiazepines, Antiepileptics, Antipsychotics, Diuretics

Disqualifiers: Epilepsy, Bipolar, Kidney disease, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

The trial aims to determine if a supplement called Hydrate Heroes can enhance brain activity, mental health, and thinking skills. Participants will consume either 6 packets or 3 packets of the supplement daily, while a control group will not receive any supplement. Individuals who are generally healthy and can attend three study visits over 12 weeks may be suitable candidates. Participants must log daily water intake and adhere to the assigned supplement plan. As an unphased trial, this study provides a unique opportunity to contribute to groundbreaking research on mental health and cognitive enhancement.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that Hydrate Heroes is generally easy to use. Some studies have examined its potential benefits for mental health, such as reducing stress and anxiety, and they report no serious side effects.

The treatment includes a drink with mushrooms, known for improving mood, suggesting it is likely safe for most people. Although detailed information on side effects is limited, its inclusion in a clinical trial indicates that experts consider it safe enough for further study.

In past experiences with similar treatments, most people did not encounter serious problems. The current trial aims to provide more information about how well people tolerate different dosages. ^{1 2 3 4 5}

Why are researchers excited about this trial's treatment?

Researchers are excited about Hydrate Heroes because it offers a refreshing approach to supporting mental health through optimal hydration. Unlike traditional medications that rely on chemical compounds, Hydrate Heroes involves consuming specialized hydration packets, making it a non-invasive option. This treatment stands out by potentially enhancing mental well-being through improved hydration, which can be a simple yet effective way to support mental health. With two different dosage options—six packets per day and three packets per day—there's flexibility for users to find what works best for them.

What evidence suggests that Hydrate Heroes might be an effective treatment for mental health?

Research shows that proper hydration can aid memory, focus, and learning, leading to clearer thinking and better mental strength. This trial studies Hydrate Heroes, a hydration supplement with mushrooms, for its potential to enhance mental wellness by reducing stress, anxiety, and depression. Studies suggest that good hydration can improve brain function and boost mood. Hydrate Heroes has received funding for its proven positive effects on both mental and physical health. These findings suggest that Hydrate Heroes could effectively enhance brain function and mental health. Participants in this trial will receive either Hydrate Heroes A (6 packets/day), Hydrate Heroes B (3 packets/day), or no intervention as a control. ^{1 2 6 7 8}

Are You a Good Fit for This Trial?

This trial is for individuals experiencing mental health issues like depression or anxiety and who may also be dehydrated. Participants should be willing to take a daily supplement, Hydrate Heroes, and undergo various tests measuring brain activity and cognitive performance.

Inclusion Criteria

Capable of providing informed consent

Fluent in English (able to read, write, speak, and understand English)

Generally healthy, without chronic medical conditions

Exclusion Criteria

Pregnant or currently breastfeeding

History of epilepsy, recurrent seizures, severe head injury, or other significant neurological disorders

Current diagnosis of major psychiatric disorders (e.g., schizophrenia, bipolar disorder, severe major depressive disorder)

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive daily doses of Hydrate Heroes and undergo EEG and physiological testing

12 weeks

Weekly visits for EEG and physiological data collection

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Hydrate Heroes

Trial Overview The study is testing the effects of 'Hydrate Heroes' on brain function and mood over 12 weeks. Participants will randomly receive either 6 packets or 3 packets daily, with their brain activity, physical responses, and self-reported mood being monitored.

How Is the Trial Designed?

Group I: Hydrate Heroes A Active Control 1 Intervention

6 packets / day

Group II: Hydrate Heroes B Active Control 1 Intervention

3 packets / day

Group III: Control Active Control 1 Intervention

Who Is Running the Clinical Trial?

University of South Florida

Lead Sponsor

Trials

433

Recruited

198,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07241260?lastUpdPost=2020-01-16_

Hydrate Heroes for Improving Brain Function & Mood The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable ...

2. trial.medpath.com trial.medpath.com/clinical-trial/8fa0d7703c27ea7d/nct07241260-hydrate-heroes-impact-brain-mood-mental-health

Hydrate Heroes for Improving Brain Function & Mood | MedPath The primary goal of this 12-week randomized controlled study is to evaluate whether daily use of Hydrate Heroes results in measurable ...

3. researchgate.net researchgate.net/publication/396875305_The_Effect_of_Hydration_and_Dehydration_on_Cognitive_Performance_and_Mental_Health

The Effect of Hydration and Dehydration on Cognitive ... Adequate hydration supports memory, attention, and learning, while fostering overall mental clarity and resilience. On the other hand, ...

4. hydrateheroes.com hydrateheroes.com/?srsltid=AfmBOopO1F-aE79OAGcZwSEZ-tAhNBRgqGYAsU68RVwWLvnzGuLx7eZk

Hydrate Heroes Mushroom-infused hydration from Hydrate Heroes can also positively impact mental wellness by reducing stress, anxiety, and depression.

5. facebook.com facebook.com/officialhydrateheroes/posts/hydrate-heroes-has-been-awarded-a-grant-for-showing-the-positive-impact-that-men/1300581935405774/

Hydrate Heroes has been awarded a grant for showing the ... Hydrate Heroes has been awarded a grant for showing the positive impact that mental and physical health Hydrate Heroes can have.

6. hydrateheroes.com hydrateheroes.com/?srsltid=AfmBOop0jzFJeFOu_n3hcVtb8Mip7NJUrFb0jo2wVS-ctTevbXM71IcW

Hydrate Heroes Mushroom-infused hydration from Hydrate Heroes can also positively impact mental wellness by reducing stress, anxiety, and depression. Hydrate Heroes ...

7. cdc.gov cdc.gov/niosh/docs/2025-107/pdfs/2025-107.pdf

NIOSH Emergency Responder Health Monitoring and ... Evaluate the physical health, behavioral health, and immunization status of response and recovery workers to determine fitness for deployment and placement in ...

8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC8585601/

Preparing for the Next Pandemic to Protect Public Mental Health This article examines current findings from the pandemic and identifies gaps in the understanding of public mental health impact and mitigation strategies.