ONC-783 for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
ONC-783-001 is a Phase I open label, dose-escalation study for evaluating the safety, pharmacokinetics (PK) and efficacy of ONC-783 as a single agent in patients with advanced/metastatic solid tumors, focusing on colorectal cancer, ovarian cancer, pancreatic cancer, or breast cancer.
Are You a Good Fit for This Trial?
This trial is for adults over 18 with advanced or metastatic pancreatic, ovarian, colorectal, or breast cancer. Participants must be in relatively good health (ECOG score ≤ 1), weigh at least 40 kg, and have a life expectancy of more than 12 weeks. They should have measurable tumors and proper organ function. Women must not be pregnant and agree to use effective contraception.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Dose Escalation Treatment
Participants receive ONC-783 via SC injection in a dose-escalation study to evaluate safety, PK, and efficacy
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- ONC-783
Trial Overview
The study tests ONC-783's safety, how the body processes it (pharmacokinetics), and its effectiveness against certain solid tumors. It's an early-stage trial (Phase I) where doses increase gradually to find the safest dose that might work.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
ONC-783 will be given by SC injection in designated dose
Find a Clinic Near You
Who Is Running the Clinical Trial?
OncoC4, Inc.
Lead Sponsor
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