← Back to Search

Radioisotope Therapy

Cohort 1 for Prostate Cancer (ACTION Trial)

Phase 1
Waitlist Available
Led By Himanshu Nagar, M.D.
Research Sponsored by Weill Medical College of Cornell University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3, 6, 12, 15, 18, 21, and 24 months.
Awards & highlights

ACTION Trial Summary

This trial is testing a new cancer treatment that combines Actinium-J591 with radiation therapy or androgen deprivation therapy.

Eligible Conditions
  • Hormone-Refractory Prostate Cancer

ACTION Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3, 6, 12, 15, 18, 21, and 24 months.
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3, 6, 12, 15, 18, 21, and 24 months. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Maximum Tolerated Dose (MTD)
Dose Limiting Toxicity (DLT) Rate
Secondary outcome measures
Change in Percentage of PSA decline
Changes in PSMA expression measured by comparison of SUV on PSMA PET scans before and after treatment
Progression Free Survival (PFS) on conventional Imaging
+1 more

ACTION Trial Design

2Treatment groups
Active Control
Group I: Cohort 1Active Control2 Interventions
Group II: Cohort 2Active Control2 Interventions

Find a Location

Who is running the clinical trial?

Weill Medical College of Cornell UniversityLead Sponsor
1,054 Previous Clinical Trials
1,316,528 Total Patients Enrolled
49 Trials studying Prostate Cancer
35,639 Patients Enrolled for Prostate Cancer
Convergent Therapeutics, Inc.UNKNOWN
Himanshu Nagar, M.D.Principal InvestigatorWeill Medical College of Cornell University
6 Previous Clinical Trials
517 Total Patients Enrolled
4 Trials studying Prostate Cancer
505 Patients Enrolled for Prostate Cancer

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are adolescents within the age range of eligibility for this medical experiment?

"The age criteria for participation in this medical trial are 18 and above, up to a maximum of 90 years."

Answered by AI

Has Cohort 2 been granted sanction by the FDA?

"There is minimal data indicating the efficacy and safety of Cohort 2, thus a score of 1 was assigned."

Answered by AI

Is recruitment for this clinical trial still open to participants?

"According to clinicaltrials.gov, this trial is not currently seeking enrollees. This study was initially uploaded on December 1st 2022 and has been amended as recently as October 3rd 2022. Although no longer enrolling participants, there are 1258 other trials that can be accessed now for potential involvement in medical research."

Answered by AI

Does my medical profile qualify me for enrollment in this experiment?

"Qualified participants must have a cancer diagnosis and be between 18 to 90 years old. Currently, the trial is in need of 24 volunteers."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
ACTInium-J591 Radionuclide Therapy in PSMA-Detected Metastatic HOrmone-Sensitive Recurrent Prostate CaNcer
2023. "ACTInium-J591 Radionuclide Therapy in PSMA-Detected Metastatic HOrmone-Sensitive Recurrent Prostate CaNcer". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05567770.
~0 spots leftby Jan 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top