18F-TPP for Membrane Potential Imaging
What You Need to Know Before You Apply
What is the purpose of this trial?
In this study, investigators propose to use PET imaging to study the pharmacokinetics of 18F-TPP and develop methods for imaging membrane potential (ΔΨT) in humans.
Who Is on the Research Team?
Georges El Fakhri, PhD, DABR
Principal Investigator
Yale University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging and Pharmacokinetics Assessment
Assessment of the pharmacokinetics of 18F-TPP using PET imaging, including potential arterial blood sampling for radioactivity analysis
Follow-up
Participants are monitored for safety and effectiveness after imaging procedures
What Are the Treatments Tested in This Trial?
Interventions
- 18F-TPP
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
PET imaging to study the pharmacokinetics of 18F-TPP and develop methods for imaging membrane potential (ΔΨT) in humans. Each scan may or may not have arterial blood sampling for measurement of the time course of radioactivity in the whole-blood, plasma and radiometabolite analysis on selected plasma samples.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Collaborator
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