Quemliclustat for Healthy Subjects
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of the study is to investigate the routes of elimination and overall mass balance of 100 mg quemliclustat containing 75 μCi \[14C\] following a single IV infusion of \[14C\]-quemliclustat in healthy adult male participants, and to quantify total radioactivity (TRA) in plasma, whole blood, urine, and feces.
Who Is on the Research Team?
Medical Director
Principal Investigator
Arcus Biosciences
Are You a Good Fit for This Trial?
This trial is for healthy adult males who don't smoke, have a BMI between 18.0 and 32.0 kg/m^2, can follow the study's rules including using contraception, and have no significant medical issues as determined by the study doctor.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single intravenous dose of 100 mg quemliclustat containing 75 μCi [14C]
Follow-up
Participants are monitored for safety and effectiveness after treatment, including quantification of total radioactivity in plasma, whole blood, urine, and feces
What Are the Treatments Tested in This Trial?
Interventions
- Quemliclustat
Trial Overview
The trial is studying how Quemliclustat, given through an IV at a dose of 100 mg with a radioactive tracer, moves through and leaves the body by measuring its presence in blood, urine, and feces after one infusion.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants will receive a single dose of \[14C\]-quemliclustat through IV infusion.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Arcus Biosciences, Inc.
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.