Sample Collection for Cancer Research

Overseen By Dan Vogl, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Abramson Cancer Center of the University of Pennsylvania

Disqualifiers: Sedation contraindication

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

150 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to collect bone marrow and blood samples to support future research on cancer and other diseases. Participants may choose to receive sedation (medication to help them relax) during the bone marrow procedure, enhancing comfort. The trial seeks to improve sample collection methods, aiding research on bone marrow diseases. Individuals with a planned bone marrow procedure for research purposes might be well-suited for this trial. As an unphased trial, it offers participants the chance to contribute to significant research that could advance the understanding and treatment of various diseases.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial team or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to improve the way we gather bone marrow and blood samples for research. Unlike current methods that might not always provide enough quality samples, this trial focuses on enhancing the collection process, which is crucial for advancing our understanding of bone marrow diseases. By refining how these samples are obtained, the trial could significantly boost translational research, potentially leading to better treatments and outcomes for patients with bone marrow conditions.

Who Is on the Research Team?

Dan Vogl, MD

Principal Investigator

Abramson Cancer Center

Are You a Good Fit for This Trial?

Inclusion Criteria

Planned procedure including a bone marrow aspirate and/or bone marrow biopsy

The procedure is planned for the purpose of obtaining a research specimen (as part of another research study or as part of this stand-alone sample collection protocol.). Procedures with a dual purpose (i.e. to obtain both clinically-indicated specimens and research specimens) are permitted, but procedures to obtain clinical specimens only are not permitted.

All subjects must provide written informed consent for the biopsy procedure, the collection of bone marrow and blood specimens for research purposes and (if planned) the administration of sedation.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Sample Collection

Collection of bone marrow aspirate/biopsy and blood specimens for research purposes, with the option of sedation during the procedure

1 day

1 visit (in-person)

Follow-up

Participants are monitored for any immediate post-procedure effects and safety

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Obtaining human tissue for basic research or biospecimen bank

How Is the Trial Designed?

Group I: Bone marrow aspirate/biopsy and blood specimens Experimental Treatment 1 Intervention

Collection of blood and bone marrow specimens for research purposes and increase the successful acquisition of correlative bone marrow samples to improve translational research in bone marrow diseases

Who Is Running the Clinical Trial?

Abramson Cancer Center of the University of Pennsylvania

Lead Sponsor

Trials

360

Recruited

108,000+

Abramson Cancer Center at Penn Medicine

Lead Sponsor

Trials

425

Recruited

464,000+