Implantoplasty for Peri-Implant Mucositis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines the effectiveness of implantoplasty, a process that smooths the surface of dental implants, in healing gum inflammation around dental implants, known as peri-implant mucositis. It compares treated implants with untreated ones, focusing on healing signs both physically and microscopically. Individuals with dental implants previously treated for peri-implantitis, who now have stable gum and bone conditions, might be suitable candidates. As an unphased trial, this study provides a unique opportunity to advance dental care techniques.
Will I have to stop taking my current medications?
If you are on significant medications for systemic conditions, like chronic anti-inflammatory drugs, antibiotics, or anticoagulants, you may not be eligible for the study. However, short-term use of pain relievers or cold medicine is allowed.
What prior data suggests that implantoplasty is safe for treating peri-implant mucositis?
Research shows that implantoplasty, a process that smooths implants, is a safe option for treating gum inflammation around implants, known as peri-implant mucositis. Although detailed information is limited, implantoplasty remains a common and generally well-tolerated dental procedure.
For peri-implant mucositis, studies indicate that nonsurgical treatments, like professional cleaning, effectively manage symptoms. These methods have been used in dental care for a long time, suggesting their safety.
While this trial doesn't specify a particular phase, the established use of implantoplasty suggests its safety. For those considering joining a clinical trial involving implantoplasty, existing research indicates it is likely safe and well-tolerated for most people.12345Why are researchers excited about this trial?
Researchers are excited about implantoplasty for peri-implant mucositis because it offers a novel approach by focusing on the mechanical modification of implant surfaces. Unlike traditional treatments, which typically involve antimicrobial therapies or surgical interventions to manage inflammation, implantoplasty aims to smooth and polish the surface of dental implants. This technique can potentially reduce bacterial accumulation and improve healing. By directly altering the implant surface, this method could enhance long-term outcomes and offer an effective adjunct or alternative to conventional treatments for managing peri-implant mucositis.
What evidence suggests that implantoplasty is effective for peri-implant mucositis?
Research shows that implantoplasty (IP) might help manage peri-implant mucositis, an inflammation around dental implants. Studies have found that treatments for this condition can prevent worsening in up to 60% of cases. The American Academy of Periodontology recommends effective management, often involving cleaning around the implant and controlling risk factors. This trial will evaluate IP, which involves smoothing the implant surface, to determine if it reduces inflammation and aids tissue healing. While more research is needed, these findings suggest that IP could be promising for treating peri-implant mucositis.13678
Who Is on the Research Team?
Andrea Ravida
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
This trial is for adults aged 18-80 in good health, with specific dental implants previously treated for peri-implantitis. Participants should have minimal bacteria on the implant, stable bone levels around it, and healthy gums. Excluded are those with active infections, certain medical conditions requiring premedication before dental visits, pregnant women or those planning pregnancy, heavy smokers, and individuals on significant drug therapy.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Experimental Peri-implant Mucositis
Participants undergo a 21-day period of experimentally induced peri-implant mucositis while wearing a stent over the implant area during routine oral health care.
Resolution of Peri-implant Mucositis
Participants undergo a 21-day period for the resolution of induced peri-implant mucositis with continued monitoring and sample collection.
Follow-up
Participants are monitored for any remaining inflammation and treated as necessary every 3-4 weeks until resolved.
What Are the Treatments Tested in This Trial?
Interventions
- Induction of experimental peri-implant mucositis
- Resolution of experimental peri-implant mucositis
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor