Follow-up Calls for Colorectal Cancer Screening

No longer recruiting at 1 trial location
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: University of Southern California
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether follow-up phone calls can increase the return rate of mailed FIT Kits, used for colorectal cancer screening. The goal is to determine if a reminder call encourages more people to complete and return their kits. One group will receive both the FIT Kit and a follow-up call, while the other will receive only the FIT Kit. The trial seeks participants aged 45-59 who are due for cancer screening and have previously returned a FIT Kit. As an unphased trial, it offers participants the chance to contribute to enhancing cancer screening processes.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on follow-up calls for returning FIT Kits, so it's unlikely that your medications will be affected.

What prior data suggests that follow-up calls are safe for increasing FIT Kit return rates?

A previous study found that adding follow-up phone calls to mailed fecal immunochemical test (FIT) kits increased the return rate of the kits. This method is simple, involves no medication, and has not been associated with any physical side effects. Phone calls are generally well-accepted in healthcare settings, with no reports of negative effects from receiving a call as part of this process. Therefore, phone call follow-ups pose no safety concerns for participants in trials like this one.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores the use of follow-up phone calls to boost colorectal cancer screening rates. Unlike standard methods that typically rely on mailing a FIT Kit and hoping patients complete it, this approach adds a personal touch by reminding and encouraging patients through a call. This could make a significant difference in participation and early detection, potentially saving more lives by catching cancer earlier. By integrating this simple yet impactful step, the trial aims to improve the effectiveness of existing screening programs.

What evidence suggests that follow-up calls are effective for increasing the return rate of FIT Kits for colorectal cancer screening?

Research shows that follow-up phone calls can increase the return rate of mailed FIT Kits, which screen for colorectal cancer. In this trial, one group of participants will receive a second FIT Kit along with a follow-up phone call to encourage its completion and return. Another group will receive only the second FIT Kit without a follow-up call. Previous studies have shown that adding phone calls and texts to mailed FIT Kits increased participation in screening programs. Specifically, when mailed FIT Kits were combined with follow-up calls, screening rates increased by 7.3% compared to the usual approach. These findings suggest that phone calls effectively encourage people to complete and return their FIT Kits, leading to higher screening rates.12467

Are You a Good Fit for This Trial?

This trial is for individuals eligible for colorectal cancer screening. Specific eligibility criteria are not provided, but typically this includes adults of a certain age range or with risk factors for colorectal cancer. Details on who can't participate are not given.

Inclusion Criteria

Previously returned a FIT Kit
I am between 45 and 59 years old.
Not sent a FIT Kit in the past 3 months
See 1 more

Exclusion Criteria

Incarcerated
I am not due for a colorectal cancer screening.
I am either younger than 45 or older than 59.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive a FIT Kit, with half receiving a follow-up call to encourage return

60 days

Follow-up

Participants are monitored for the return rate of the FIT Kit

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Phone call
Trial Overview The study is testing if follow-up phone calls increase the return rate of mailed FIT Kits used in colorectal cancer screening. Participants are split into two groups: one receives a reminder call, while the other does not.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: FIT Kit + Phone CallExperimental Treatment2 Interventions
Group II: FIT Kit OnlyActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Southern California

Lead Sponsor

Trials
956
Recruited
1,609,000+

Citations

Effectiveness and Cost-effectiveness of Mailed FIT in a Safety ...Mailed FIT is an effective and cost-effective population health strategy for CRC screening in vulnerable patients.
The Reach of Calls and Text Messages for Mailed FIT ...Mailed fecal immunochemical test (FIT) outreach can improve colorectal cancer screening participation. We assessed the reach and effectiveness of adding ...
Increased Colorectal Cancer Screening Sustained with ...Organized mailed FIT outreach significantly increased colorectal cancer screening over multiple years in this safety-net health system.
Mailed Outreach and Patient Navigation for Colorectal ...A mailed FIT outreach and patient navigation program led to a significant 7.3–percentage point increase in colorectal cancer (CRC) screening over usual care.
Effective strategies for Fecal Immunochemical Tests (FIT ...This rapid review systematically reviewed and synthesized evidence on the effectiveness of Fecal Immunochemical Test (FIT) programs in increasing CRC screening.
Interventions to Increase Follow-Up of Abnormal Stool ...Interventions to increase follow-up of abnormal stool-based colorectal cancer screening tests in safety net settings: a systematic review.
Colorectal Cancer Screening After Sequential Outreach ...This cohort study examines colorectal cancer (CRC) screening completion by race and ethnicity, age, and sex in an integrated health care ...
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