THC (Dronabinol) for Sleep Issues in Cannabis Users
What You Need to Know Before You Apply
What is the purpose of this trial?
The investigators will test the effects of 10-60mg dronabinol (oral THC) on sleep in non-frequent and frequent cannabis users.
Who Is on the Research Team?
Steven A Shea, PhD
Principal Investigator
Oregon Health and Science University
Are You a Good Fit for This Trial?
This trial is for adults who have used cannabis less than 10 times ever or those using it more than three times a week for the last three months. It's not suitable for individuals with cardiovascular disease, seizure history, certain psychiatric conditions, severe liver issues, drug dependencies (excluding THC), or those on medications including antidepressants.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Acclimation and Baseline
Participants undergo an acclimation and baseline night of sleep to establish baseline sleep patterns
Treatment
Participants receive a single dose of 10-60mg dronabinol or placebo, with sleep and cognitive performance measured
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Dronabinol
Dronabinol is already approved in United States, Canada for the following indications:
- HIV/AIDS-induced anorexia
- Chemotherapy-induced nausea and vomiting
- Sleep apnea
- HIV/AIDS-induced anorexia
- Chemotherapy-induced nausea and vomiting
- HIV/AIDS-induced anorexia
- Chemotherapy-induced nausea and vomiting
Find a Clinic Near You
Who Is Running the Clinical Trial?
Oregon Health and Science University
Lead Sponsor