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Epinephrine for Diabetes (Epineprhine Trial)
Epineprhine Trial Summary
This trial will study the effects of epinephrine on the body, specifically how it regulates function and inflammation.
Epineprhine Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowEpineprhine Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 4 trial • 22 Patients • NCT04065451Epineprhine Trial Design
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Who is running the clinical trial?
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- You have a fever higher than 38.0 degrees Celsius.Your hematocrit level is lower than 32%.Your white blood cell count is below 3,000 or above 14,000.You have kidney failure.Your alkaline phosphatase level is higher than 150 units per liter.People who are healthy and between 18 and 55 years old.You currently smoke or use tobacco products.Your body mass index is higher than 21 kg/m2.You had a stroke or were hospitalized for a stroke within the 4 weeks before joining the study.Your liver function tests show high levels of SGOT and SGPT, which may indicate a problem with your liver.You are taking blood-thinning medication, have anemia, or have a known tendency to bleed.You have a history of severe, uncontrolled high blood pressure, heart problems, or strokes.Your blood pressure is very high and not well controlled (above 160/100).You have a serious heart condition like heart failure or irregular heartbeat.You have liver failure or jaundice.Your total bilirubin level is higher than 2 mg/dl.Your kidneys are not working well, as indicated by a test called eGFR.You have HIV, Hepatitis B, or Hepatitis C.If you are over 40 years old, you have shown an abnormal heart response during an exercise test.
- Group 1: Epinephrine infusion-0.015ug/kg/min
- Group 2: Epinephrine infusion-0.06 ug/kg/min
- Group 3: Epinephrine infusion-0.03 ug/kg/min
- Group 4: Saline infusion
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
For what purpose is Epinephrine typically employed?
"Epinephrine can be used to treat low blood pressure, an unresponsive slow heart rate, and an abnormal dilation of the pupil."
Are there any open enrollment opportunities for this research project?
"If you consult clinicaltrials.gov, you'll see that this study is still looking for participants. It was originally posted on June 1st, 2016 but was updated most recently on April 8th, 2022."
What is the precedent for Epinephrine clinical trials?
"As of right now, there are 33 on-going Epinephrine trials with 5 in the final Phase 3. A majority of these studies are centred in Baltimore, Maryland, but there are 52 locations in total running these Epinephrine trials."
If a potential test subject is younger than 65, will they still be able to participate in this experiment?
"The age range for people who can enroll in this trial are those who are 18 years old or older, but younger than 55 years old."
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