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Electrolyte Supplement

Magnesium Sulfate in the first hour for Asthma

Q: Are individuals older than 65 years of age eligible to participate in this clinical trial?

This clinical trial welcomes participants above 5 years of age and below 17 years old.

Q: What is the current number of participants being enrolled in this clinical research study?

Indeed, details on clinicaltrials.gov highlight the ongoing recruitment for this specific trial. The commencement date of this study was documented as 11/30/2023 and the latest revision occurred on 3/4/2024. A total of 100 individuals are sought to participate in this trial across a single site.

Q: Which individuals meet the criteria for inclusion in this research?

To qualify for this study, children and teenagers aged 5 to 17 with <a href="https://www.withpower.com/clinical-trials/asthma">asthma</a> are sought. Additionally, eligible participants must have a "Moderate" respiratory score upon emergency department presentation and have English-speaking parent(s) or caregiver(s).

Q: Are there any available slots for patients to participate in this research study?

Based on information from clinicaltrials.gov, this investigation is currently in search of suitable participants. The trial's initial posting was on November 30th, 2023, with the latest update made on March 4th, 2024.

Phase < 1

Recruiting

Led By Ryan McKee, MD

Research Sponsored by University of Oklahoma

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up time of initiation of therapy to discharge from the hospital, up to 2 weeks

Awards & highlights

Study Summary

This trial is trying to find out if giving magnesium sulfate early to children with moderate asthma attacks can help prevent them from being admitted to the hospital, reduce the time they spend in the emergency room and hospital

Who is the study for?

This trial is for children aged 5-17 who come to the emergency department with a moderate level of breathing difficulty due to asthma. Their parents or caregivers must speak English. It's not suitable for those outside this age range or with different levels of respiratory distress.Check my eligibility

What is being tested?

The study is testing if giving magnesium sulfate within the first hour of arriving at the hospital helps kids with moderate asthma attacks by reducing their stay in the ER, avoiding admission, and lessening the need for intensive care or breathing support.See study design

What are the potential side effects?

Magnesium sulfate can cause side effects like flushing, sweating, nausea, vomiting, headache, dizziness, and sleepiness. In rare cases it might affect heart rate and blood pressure.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ time of initiation of therapy to discharge from the hospital, up to 2 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~time of initiation of therapy to discharge from the hospital, up to 2 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and time of initiation of therapy to discharge from the hospital, up to 2 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Length of Stay in Patients who receive IV Magnesium within the first hour (experimental group) vs control group

Secondary outcome measures

Evaluate the need for respiratory support in patients receiving magnesium sulfate within the first hour (experimental group) vs control group

Side effects data

From 2012 Phase 4 trial • 200 Patients • NCT01342510

30%

Pain with injection of propofol

100%

80%

60%

40%

20%

Study treatment Arm

Lidocaine/Magnesium

Control

Lidocaine

Magnesium

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Magnesium Sulfate in the first hourExperimental Treatment1 Intervention

These patients will receive 40-50 mg/kg IV magnesium sulfate within the first hour of treatment alongside all first line asthma exacerbation therapies (ie inhaled beta agonists, IV steroids).

Group II: No Magnesium SulfatePlacebo Group1 Intervention

These patients will not receive IV magnesium sulfate within the first hour of treatment but may receive it later if the provider feels it is clinically necessary.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of OklahomaLead Sponsor

455 Previous Clinical Trials

95,823 Total Patients Enrolled

1 Trials studying Asthma

20 Patients Enrolled for Asthma

Ryan McKee, MDPrincipal InvestigatorUniversity of Oklahoma

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals older than 65 years of age eligible to participate in this clinical trial?

"This clinical trial welcomes participants above 5 years of age and below 17 years old."

Answered by AI

What is the current number of participants being enrolled in this clinical research study?

"Indeed, details on clinicaltrials.gov highlight the ongoing recruitment for this specific trial. The commencement date of this study was documented as 11/30/2023 and the latest revision occurred on 3/4/2024. A total of 100 individuals are sought to participate in this trial across a single site."

Answered by AI

Which individuals meet the criteria for inclusion in this research?

"To qualify for this study, children and teenagers aged 5 to 17 with asthma are sought. Additionally, eligible participants must have a "Moderate" respiratory score upon emergency department presentation and have English-speaking parent(s) or caregiver(s)."

Answered by AI

Are there any available slots for patients to participate in this research study?

"Based on information from clinicaltrials.gov, this investigation is currently in search of suitable participants. The trial's initial posting was on November 30th, 2023, with the latest update made on March 4th, 2024."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation

2023. "Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06137040.