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Hyaluronidase for Drug Safety
Phase < 1
Waitlist Available
Led By Murad Alam, MD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Age 18 and over
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 weeks
Awards & highlights
Study Summary
This trial is testing how much hyaluronidase to use when getting filler injections - too much can cause problems.
Who is the study for?
This trial is for adults over 18 in good health who can give informed consent. It's not for those with a tendency to form abnormal scars, tattoos or scars where the treatment will be given, allergies to hyaluronic acid, under 18s, pregnant or breastfeeding individuals, those unable to understand the study or give consent, and anyone who has used Accutane recently.Check my eligibility
What is being tested?
The study is testing how much hyaluronidase should be used to reduce or remove hyaluronic acid fillers safely. Hyaluronidase is an enzyme that breaks down filler material injected into the skin.See study design
What are the potential side effects?
Potential side effects of using hyaluronidase may include swelling, bruising at the injection site, allergic reactions if sensitive to the enzyme and possibly uneven results if too much filler is dissolved.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 18 years old or older.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Dose of hyaluronidase injected until the filler is no longer detectable
Trial Design
1Treatment groups
Experimental Treatment
Group I: Dose of HyaluronidaseExperimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Hyaluronidase
2007
Completed Phase 4
~370
Find a Location
Who is running the clinical trial?
Northwestern UniversityLead Sponsor
1,585 Previous Clinical Trials
917,226 Total Patients Enrolled
Murad Alam, MDPrincipal InvestigatorNorthwestern University
69 Previous Clinical Trials
2,575 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I am willing and able to give consent for my tissue use and communicate with my doctor.I am 18 years old or older.I understand the study and can give my consent.I have not used Accutane in the last 6 months.I have tattoos or scars on my upper medial arms.I am in good health overall.I am younger than 18 years old.
Research Study Groups:
This trial has the following groups:- Group 1: Dose of Hyaluronidase
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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