Academic Detailing for HIV Prevention

(ADOPT-PrEP Trial)

Overseen By Carly Guss, MD, MPH

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Boston Children's Hospital

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a method called academic detailing to determine if it helps pediatricians better prescribe HIV prevention medication, known as PrEP, to teens and young adults. Academic detailing involves trained educators having one-on-one conversations with doctors to encourage changes in medical practice. The trial aims to assess the practicality of this approach and its impact on how often doctors recommend PrEP and how patients use it. Pediatricians at specific Boston medical centers are the focus of this study. As an unphased trial, this study offers participants the chance to contribute to innovative educational methods that could enhance healthcare practices.

Will I have to stop taking my current medications?

The trial information does not specify whether participants must stop taking their current medications.

What prior data suggests that this academic detailing technique is safe for pediatricians?

Research has shown that academic detailing is safe and well-tolerated. This approach involves one-on-one educational sessions to improve healthcare practices. Studies have found it effectively increases awareness and knowledge, particularly in areas like HIV prevention and treatment. As an educational method rather than a medication or medical procedure, it has no reported side effects, making it a low-risk option for participants. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about academic detailing for HIV prevention because it offers a personalized approach to educating healthcare providers, like pediatricians, about the latest prevention strategies. Unlike standard educational materials or training sessions, academic detailing involves one-on-one interactions with experts who tailor the information to the specific needs and context of the healthcare provider. This method has the potential to improve the adoption of HIV prevention practices by making them more relevant and actionable for providers, ultimately enhancing patient care.

What evidence suggests that academic detailing is effective for changing pediatricians' prescribing behavior for HIV prevention?

Studies have shown that academic detailing effectively increases the prescribing of pre-exposure prophylaxis (PrEP) for HIV prevention. This approach involves personalized educational sessions that help doctors understand and use new treatments. Research indicates that academic detailing has improved routine HIV testing and awareness among healthcare providers. By enhancing knowledge and changing prescribing habits, academic detailing aims to make PrEP more accessible to those who need it. This method has succeeded in places like New York City and New England, leading to better care and prevention outcomes. ^{1 3 5 6 7}

Are You a Good Fit for This Trial?

This trial is for primary care providers at Boston Children's Hospital Adolescent/Young Adult Medicine, Martha Eliot Health Center, or Children's Hospital Primary Care Center. There are no specific exclusion criteria mentioned.

Inclusion Criteria

Primary care provider at one of our 3 study sites (Boston Children's Hospital Adolescent/Young Adult Medicine, Martha Eliot Health Center, Children's Hospital Primary Care Center)

Exclusion Criteria

Not applicable.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Academic Detailing Intervention

Pediatric providers participate in academic detailing sessions to improve PrEP prescribing practices

1 month

2 academic detailing visits

Follow-up

Participants are monitored for changes in PrEP prescriptions, persistence, and HIV testing

6 months

What Are the Treatments Tested in This Trial?

Interventions

• Academic detailing

Trial Overview The study tests academic detailing as a method to improve how pediatricians prescribe PrEP (a medication to prevent HIV) to adolescents and young adults. It involves personalized education sessions with trained educators aiming to change clinician behavior.

How Is the Trial Designed?

Group I: pediatricians Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Boston Children's Hospital

Lead Sponsor

Trials

801

Recruited

5,584,000+

Published Research Related to This Trial

Effective HIV prevention today requires a combination of behavioral, biomedical, and structural strategies, including consistent condom use, reducing the number of sexual and needle-sharing partners, male circumcision, and antiretroviral treatment.

Despite the identification of 144 effective behavioral prevention programs, scaling these initiatives outside the United States has been limited, highlighting the need for integrating behavioral strategies with biomedical innovations to enhance overall effectiveness in HIV prevention.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The past, present, and future of HIV prevention: integrating behavioral, biomedical, and structural intervention strategies for the next generation of HIV prevention. Rotheram-Borus, MJ., Swendeman, D., Chovnick, G.[2022]

Citations

1. sciencedirect.com sciencedirect.com/science/article/pii/S0749379721003640

Academic Detailing to Increase Prescribing of HIV Pre ... This review provides an overview of academic detailing and how it is currently being used to increase pre-exposure prophylaxis prescribing.

2. paetc.org paetc.org/our-programs/prep-academic-detailing/

PrEP Academic Detailing Other possible HIV prevention outcomes for PrEP AD are: implementation of routine HIV testing; thorough appropriate sexual history taking; STD screening ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC3873859/

Scaling up routine HIV testing at specialty clinics These findings demonstrate that academic detailing-style educational sessions can enhance rates of routine HIV testing for public safety-net health system ...

4. academic.oup.com academic.oup.com/cid/article/68/5/860/5055345

Public Health Detailing for Human Immunodeficiency Virus ... We describe the novel application of detailing to increase PrEP prescribing and related care in New York City and New England.

5. digitalcommons.fiu.edu digitalcommons.fiu.edu/cgi/viewcontent.cgi?article=1012&context=cnhs-studentprojects

Health Provider Academic Detailing to increase knowledge ... Included in this document is a comprehensive overview of the project including a review of the background and literature to support the quality.

6. dph.sc.gov dph.sc.gov/diseases-conditions/infectious-diseases/hivaids/sti-hiv-and-viral-hepatitis-academic-detailing

STI, HIV, and Viral Hepatitis Academic Detailing It increases awareness and knowledge regarding sexually transmitted infections (STIs), HIV, and viral hepatitis (VH) screening, prevention, and treatment. It ...

7. mihivsti.com mihivsti.com/wp-content/uploads/301-Academic-Detailing-as-a-Tool-for-HIV-STI-Prevention.pdf

Academic Detailing as a Tool for HIV/STI Prevention: ➢ Awareness of current HIV/STI data trends as well as screening & testing guidelines. ➢ Realistic education about PrEP, including navigation and paying for.