Simon Horslen | The Organ Donation and ...

Dr. Simon Horslen, MD

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UPMC Children's Hospital of Pittsburgh

Studies Liver Dysfunction
Studies Liver Disease
9 reported clinical trials
8 drugs studied

Affiliated Hospitals

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UPMC Children's Hospital Of Pittsburgh
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Seattle Children's Hospital

Clinical Trials Simon Horslen, MD is currently running

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Primary Sclerosing Cholangitis in Children

for undefined

Primary sclerosing cholangitis (PSC) is a rare liver disease that damages the liver's bile ducts. Bile ducts are tiny tubes that carry bile from the liver to the small intestine. Bile is a liquid produced by the liver that helps us absorb and use the nutrients in the food we eat. In people with PSC, the bile backs up into the liver and will damage it, causing scarring of the liver. The purposes of this study are to: * Collect medical and other data to learn more about PSC, how it progresses, and identify factors that may cause the disease to progress more quickly. * Ask questions about how PSC symptoms affect your child's life to learn more about its impact on your child's daily functioning * Children with PSC who are seen at one of the participating clinical sites in the Childhood Liver Disease Research Network (ChiLDReN) will be asked to contribute information, DNA, and other specimens. The information and specimens will be available to investigators to carry out approved research aimed at learning more about the possible causes and long-term effects of PSC.
Recruiting1 award N/A10 criteria
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Database

for Biliary Atresia

Biliary atresia, idiopathic neonatal hepatitis, and specific genetic cholestatic conditions are the most common causes of jaundice and hyperbilirubinemia that continue beyond the newborn period. The long term goal of the Childhood Liver Disease Research Network (ChiLDReN) is to establish a database of clinical information and plasma, serum, and tissue samples from cholestatic children to facilitate research and to perform clinical, epidemiological and therapeutic trials in these important pediatric liver diseases.
Recruiting1 award N/A3 criteria

More about Simon Horslen, MD

Clinical Trial Related18 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 4 Active Clinical Trials
Treatments Simon Horslen, MD has experience with
  • Maralixibat
  • Teduglutide
  • Genetic Material Collection
  • Body Fluid Sample Collection
  • No Investigational New Treatment
  • Observational Study

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