Dr. Jean M. Tersak
Claim this profileChildren's Hospital of Pittsburgh of UPMC
Expert in Cancer
Expert in Neuroblastoma
43 reported clinical trials
99 drugs studied
Area of expertise
1Cancer
Global LeaderStage I
Stage IV
Stage II
2Neuroblastoma
Global LeaderMYC positive
Stage IV
MYC negative
Affiliated Hospitals
Clinical Trials Jean M. Tersak is currently running
Triptorelin
for Cancer
This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with an alkylating agents. Alkylating agents are part of standard chemotherapy, but may cause damage to the ovaries. If the ovaries are not working well or completely shut down, then it will be difficult or impossible to get pregnant in the future. Triptorelin works by blocking certain hormones and causing the ovaries to slow down or pause normal activity. The triptorelin used in this study stays active in the body for 24 weeks or about 6 months after a dose is given. After triptorelin is cleared from the body, the ovaries resume normal activities. Adding triptorelin before the start of chemotherapy treatment may reduce the chances of damage to the ovaries.
Recruiting2 awards Phase 34 criteria
Chemotherapy
for Cancer
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
Recruiting2 awards Phase 326 criteria
More about Jean M. Tersak
Clinical Trial Related8 years of experience running clinical trials · Led 43 trials as a Principal Investigator · 14 Active Clinical TrialsTreatments Jean M. Tersak has experience with
- Etoposide
- Cyclophosphamide
- Cytology Specimen Collection Procedure
- Laboratory Biomarker Analysis
- Carboplatin
- Doxorubicin Hydrochloride
Breakdown of trials Jean M. Tersak has run
Cancer
Neuroblastoma
Lymphoma
Osteosarcoma
Rhabdomyosarcoma
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