Genetic Collection for Liver Disease

Recruiting at 10 trial locations

Overseen By Melissa Sexton, BBA

Age: < 65

Sex: Any

Trial Phase: Academic

Sponsor: Arbor Research Collaborative for Health

Disqualifiers: Deceased, Eligibility violation, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

2230 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to collect DNA from blood or saliva samples to support current and future research on liver diseases in children. The goal is to help researchers better understand genetic factors related to these conditions. This trial suits children who previously participated in specific studies, such as PROBE or BASIC, and continue to receive care at the clinical site. Participants should have agreed to DNA collection during those studies but have not yet provided a sample.

As an unphased trial, participation offers a unique opportunity to contribute to groundbreaking research that could enhance future treatments for liver diseases in children.

Do I need to stop my current medications for this trial?

The trial does not specify whether you need to stop taking your current medications. It involves only a one-time collection of blood or saliva samples for DNA extraction.

Why are researchers excited about this trial?

Researchers are excited about the Genetic Collection Protocol because it aims to gather comprehensive genetic data that could revolutionize how we understand and treat various genetic conditions. Unlike current approaches, which often focus on symptomatic treatment, this protocol seeks to identify underlying genetic factors that contribute to diseases. By collecting and analyzing a vast array of genetic information, researchers hope to uncover new insights that could lead to more targeted and effective therapies in the future. This approach could pave the way for personalized medicine, tailoring treatments to an individual's unique genetic makeup.

Who Is on the Research Team?

Katrina Loh, MD

Principal Investigator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Lisa Henn, PhD

Principal Investigator

Arbor Research Collaborative for Health

Ed Doo, MD

Principal Investigator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

John Magee, MD

Principal Investigator

University of Michigan

Are You a Good Fit for This Trial?

Inclusion Criteria

I am still being seen by my doctor at the clinic.

I am a child participating in this study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Sample Collection

One-time collection of whole blood or saliva samples for DNA extraction and storage

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after sample collection

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Genetic Collection

Who Is Running the Clinical Trial?

Arbor Research Collaborative for Health

Lead Sponsor

Trials

21

Recruited

35,500+