Dr. Rose Khavari, MD
Claim this profileHouston Methodist Hospital
Studies Overactive Bladder
Studies Neurogenic Bladder
5 reported clinical trials
4 drugs studied
Affiliated Hospitals
Clinical Trials Rose Khavari, MD is currently running
Non-Invasive Brain Stimulation
for Neurogenic Bladder in MS
Neurogenic overactive bladder (NOAB), characterized by urinary frequency, urgency or urgency incontinence symptoms occurring during the storage phase of the bladder, is the most common urinary complaint in multiple sclerosis (MS). Current management options for NOAB in MS have limited efficacy and considerable adverse effects, which underscores the significance of this study and highlights the need for better, less invasive therapies. This novel study investigates brain therapeutic targets that could shift the focus of NOAB management in MS from a bladder-centric focus to brain restoration; specifically modulating the brain regions identified in the prior functional magnetic resonance imagining studies. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation that can modulate neurons (excite or inhibit) to improve the connectivity of the regions of interest (ROI). The preliminary data demonstrate, for the first time, significant improvement in bladder symptoms in ten women with MS who have voiding dysfunction following multifocal transcranial magnetic stimulation without any treatment-related adverse effects. This randomized double-blind, sham-controlled single center clinical trial with an optional open-label extension (OLE) phase is designed to evaluate the effects of targeted rTMS in women with MS and NOAB by investigating restorative reorganization of brain function The main purpose of this study is to determine the effects of individualized repetitive Transcranial Magnetic Stimulation (rTMS) for improving overactive bladder symptoms such as urinary frequency and urgency with or without incontinence in individuals with multiple sclerosis (MS). Patients will undergo initial screening that includes a demographics information, physical exam, past medical and surgical history, medication list, urine pregnancy test (female subjects with childbearing potential), and completion of questionnaires to confirm the eligibility of patients. All eligible patients will be required to complete a functional MRI scan followed by locating the regions of interest through neural navigation system and finally receiving 10 treatment sessions. Since this is a randomized trial, some patients will receive active treatment/ therapy sessions while others will only receive sham or placebo treatments. The total duration to complete all treatment sessions and follow up visits is approximately 4-5 months.
Recruiting0 awards N/A6 criteria
rTMS
for Overactive Bladder
This trial uses a non-invasive treatment with magnetic fields to help adults with overactive bladder. The magnetic pulses aim to normalize brain activity and improve bladder control. The study will measure changes in symptoms and brain activity over time.
Recruiting1 award N/A
More about Rose Khavari, MD
Clinical Trial Related2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Rose Khavari, MD has experience with
- Magstim Rapid2 System
- DiagnosticTest
- AMS 800 Artificial Urinary Sphincter
- RTMS
Breakdown of trials Rose Khavari, MD has run
Overactive Bladder
Neurogenic Bladder
Multiple Sclerosis
Bladder Exstrophy
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Rose Khavari, MD specialize in?
Rose Khavari, MD focuses on Overactive Bladder and Neurogenic Bladder. In particular, much of their work with Overactive Bladder has involved treating patients, or patients who are undergoing treatment.
Is Rose Khavari, MD currently recruiting for clinical trials?
Yes, Rose Khavari, MD is currently recruiting for 2 clinical trials in Houston Texas. If you're interested in participating, you should apply.
Are there any treatments that Rose Khavari, MD has studied deeply?
Yes, Rose Khavari, MD has studied treatments such as Magstim Rapid2 System, DiagnosticTest, AMS 800 Artificial Urinary Sphincter.
What is the best way to schedule an appointment with Rose Khavari, MD?
Apply for one of the trials that Rose Khavari, MD is conducting.
What is the office address of Rose Khavari, MD?
The office of Rose Khavari, MD is located at: Houston Methodist Hospital, Houston, Texas 77030 United States. This is the address for their practice at the Houston Methodist Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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