Dr. Navid Hafez, MD
Claim this profileYale University
Expert in Cystic Tumor
Studies Cancer
13 reported clinical trials
34 drugs studied
Area of expertise
1Cystic Tumor
Global LeaderStage IV
Stage III
KRAS positive
2Cancer
Stage IV
Stage III
KRAS positive
Affiliated Hospitals
Clinical Trials Navid Hafez, MD is currently running
Ipatasertib + Chemotherapy
for Cancer
This phase II ComboMATCH treatment trial tests the usual treatment of chemotherapy (paclitaxel) plus ipatasertib in patients with solid tumor cancers that that cannot be removed by surgery (unresectable), has spread to nearby tissue or lymph nodes (locally advanced) or from where it first started (primary site) to other places in the body (metastatic), and has PTEN and AKT genetic changes. Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Targeted therapy, such as Ipatasertib, may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. The addition of ipatasertib to paclitaxel in solid tumors with PTEN and AKT genetic changes could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression). Researchers hope to learn if paclitaxel plus ipatasertib will shrink this type of cancer or stop its growth.
Recruiting1 award Phase 2
Nivolumab
for Cancer
This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Recruiting1 award Phase 120 criteria
More about Navid Hafez, MD
Clinical Trial Related7 years of experience running clinical trials · Led 13 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Navid Hafez, MD has experience with
- Pembrolizumab
- Olaparib
- Paclitaxel
- Sotorasib
- Ipatasertib
- Palbociclib
Breakdown of trials Navid Hafez, MD has run
Cystic Tumor
Cancer
Solid Tumors
Ovarian Cancer
Endometrial Cancer
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