Maria TIRONA | Section Chief, Division ...

Dr. Maria R. Tria Tirona

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Edwards Comprehensive Cancer Center

Expert in Lung Cancer
Expert in Non-Small Cell Lung Cancer
36 reported clinical trials
96 drugs studied

Area of expertise

1

Lung Cancer

Global Leader

Maria R. Tria Tirona has run 19 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II
2

Non-Small Cell Lung Cancer

Global Leader

Maria R. Tria Tirona has run 12 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II

Affiliated Hospitals

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Edwards Comprehensive Cancer Center

Clinical Trials Maria R. Tria Tirona is currently running

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Eribulin + Chemotherapy

for Bladder Cancer

This phase III trial compares the usual chemotherapy treatment to eribulin plus gemcitabine in treating patients with urothelial cancer that has spread from where it first started (primary site) to other places in the body (metastatic). Chemotherapy drugs, such as eribulin, gemcitabine, docetaxel, paclitaxel, and sacituzumab govitecan work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial aims to see whether adding eribulin to standard of care chemotherapy may work better in treating patients with metastatic urothelial cancer.

Recruiting

2 awards

Phase 3

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Selumetinib + Olaparib

for Ovarian and Endometrial Cancer

This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.

Recruiting

1 award

Phase 2

More about Maria R. Tria Tirona

Clinical Trial Related

9 years of experience running clinical trials · Led 36 trials as a Principal Investigator · 11 Active Clinical Trials

Treatments Maria R. Tria Tirona has experience with

  • Pembrolizumab
  • Carboplatin
  • Paclitaxel
  • Biospecimen Collection
  • Gemcitabine Hydrochloride
  • Nivolumab

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