2000 Participants Needed

Blood Sample Collection for Cancer Detection

Recruiting at 771 trial locations
MW
Overseen ByMarie Wood, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Alliance for Clinical Trials in Oncology
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to develop tests for early cancer detection by collecting and studying blood and tissue samples from individuals with and without cancer. By comparing these samples, researchers hope to find clues that could lead to new, earlier detection methods. The trial involves completing a questionnaire and providing blood samples, with tissue samples collected from those diagnosed with cancer. Individuals with a current cancer diagnosis, a strong suspicion of cancer, or no cancer at all, who are willing to provide blood samples, may be suitable for this trial. Participants must be able to read and understand English or Spanish.

As an unphased trial, this study offers participants the chance to contribute to groundbreaking research that could revolutionize early cancer detection.

Do I have to stop taking my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It would be best to discuss this with the study team or your doctor.

What prior data suggests that this biospecimen collection is safe?

Earlier studies have shown that collecting blood and tissue samples is safe for research. Safety measures include careful handling, storage, and quality checks to ensure proper use of the samples. Taking blood samples is usually easy for participants and involves minimal risk, similar to routine blood tests at a doctor's office.

Answering questionnaires in medical studies is also safe. These are simply a series of questions that help researchers gather important information. Overall, both collecting samples and answering questions in studies like this are considered safe and low-risk for participants.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a novel approach to early cancer detection by collecting and analyzing blood samples. Unlike traditional diagnostic methods that often rely on imaging or invasive procedures, this trial aims to identify cancer biomarkers through a simple blood test. This non-invasive method could potentially lead to earlier detection of cancer, improving treatment outcomes and patient quality of life. By comparing samples from individuals with and without cancer, researchers hope to refine tests that could become a standard tool for early diagnosis in the future.

Who Is on the Research Team?

MW

Marie Wood, MD

Principal Investigator

University of Colorado, Denver

Are You a Good Fit for This Trial?

Inclusion Criteria

Histologic documentation: Histologically confirmed diagnosis of invasive cancer
Stage: Stage I-IV per American Joint Committee on Cancer (AJCC) 7th edition, with the exception of patients with leukemia, lymphoma, and multiple myeloma
For leukemia: Type (chronic lymphocytic leukemia [CLL], chronic myeloid leukemia [CML], acute lymphoblastic lymphoma [ALL], acute myeloid leukemia [AML])
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Baseline

Participants complete a questionnaire and undergo collection of blood samples at registration

1 week
1 visit (in-person)

Follow-up

Participants undergo collection of blood samples and possibly tissue samples at 12 months after registration

12 months
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • Biospecimen Collection
  • Questionnaire Administration
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Screening (questionnaire, biospecimen collection)Experimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Alliance for Clinical Trials in Oncology

Lead Sponsor

Trials
521
Recruited
224,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

Citations

1.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/25688116/
Leveraging biospecimen resources for discovery or ...Validation of early detection cancer biomarkers has proven to be disappointing when initial promising claims have often not been reproducible in diagnostic ...
NCI Best Practices for Biospecimen Resourcessamples (NCI Best Practices working definition). Biospecimen resource. A collection of human specimens and associated data for research purposes, the.
Study Details | NCT05334069 | Collecting Blood Samples ...This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and ...
Study and Biospecimen Team and Analyst CoreThe collected blood samples will allow researchers to study how genetics and various blood measures, such as cholesterol, are related to health and cancer risk ...
Collecting, Storing, Using, and Distributing Biospecimens - NCBIThe document covers repository organization, management, and facilities; storage equipment and environment; quality assurance and quality control; safety; ...
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