Dr. Mahvish Muzaffar
Claim this profileEast Carolina University
Studies Breast Cancer
Studies Breast cancer
10 reported clinical trials
29 drugs studied
Area of expertise
1Breast Cancer
HER2 negative
ER negative
PR negative
2Breast Cancer
HER2 negative
ER negative
PR negative
Affiliated Hospitals
Clinical Trials Mahvish Muzaffar is currently running
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
Blood Sample Collection
for Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.
Recruiting1 award N/A9 criteria
More about Mahvish Muzaffar
Clinical Trial Related2 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Mahvish Muzaffar has experience with
- Biospecimen Collection
- Fluorouracil
- Questionnaire Administration
- Irinotecan
- Bevacizumab
- Leucovorin Calcium
Breakdown of trials Mahvish Muzaffar has run
Breast Cancer
Breast cancer
Colorectal Cancer
Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mahvish Muzaffar specialize in?
Mahvish Muzaffar focuses on Breast Cancer and Breast cancer. In particular, much of their work with Breast Cancer has involved HER2 negative patients, or patients who are ER negative.
Is Mahvish Muzaffar currently recruiting for clinical trials?
Yes, Mahvish Muzaffar is currently recruiting for 4 clinical trials in Greenville North Carolina. If you're interested in participating, you should apply.
Are there any treatments that Mahvish Muzaffar has studied deeply?
Yes, Mahvish Muzaffar has studied treatments such as Biospecimen Collection, Fluorouracil, Questionnaire Administration.
What is the best way to schedule an appointment with Mahvish Muzaffar?
Apply for one of the trials that Mahvish Muzaffar is conducting.
What is the office address of Mahvish Muzaffar?
The office of Mahvish Muzaffar is located at: East Carolina University, Greenville, North Carolina 27834 United States. This is the address for their practice at the East Carolina University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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