Mahvish MUZAFFAR | Professor (Associate ...

Dr. Mahvish Muzaffar

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East Carolina University

Studies Breast Cancer
Studies Breast cancer
10 reported clinical trials
29 drugs studied

Area of expertise

1

Breast Cancer

Mahvish Muzaffar has run 5 trials for Breast Cancer. Some of their research focus areas include:

HER2 negative
ER negative
PR negative
2

Breast Cancer

Mahvish Muzaffar has run 5 trials for Breast cancer. Some of their research focus areas include:

HER2 negative
ER negative
PR negative

Affiliated Hospitals

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East Carolina University

Clinical Trials Mahvish Muzaffar is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

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Blood Sample Collection

for Cancer Detection

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.

Recruiting

1 award

N/A

9 criteria

More about Mahvish Muzaffar

Clinical Trial Related

3 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Mahvish Muzaffar has experience with

  • Biospecimen Collection
  • Fluorouracil
  • Questionnaire Administration
  • Irinotecan
  • Bevacizumab
  • Leucovorin Calcium

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