Dr. Leslie Bradford, MD
Claim this profileMaine Medical Center- Scarborough Campus
Expert in Ovarian Cancer
Studies Parotid Gland Cancer
22 reported clinical trials
52 drugs studied
Area of expertise
1Ovarian Cancer
Global LeaderStage IV
BRCA1 positive
KRAS positive
2Parotid Gland Cancer
Stage IV
Stage III
Stage I
Affiliated Hospitals
Clinical Trials Leslie Bradford, MD is currently running
Mirvetuximab + Bevacizumab
for Ovarian Cancer
GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.
Recruiting2 awards Phase 3
Selumetinib + Olaparib
for Ovarian and Endometrial Cancer
This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.
Recruiting1 award Phase 2
More about Leslie Bradford, MD
Clinical Trial Related2 years of experience running clinical trials · Led 22 trials as a Principal Investigator · 11 Active Clinical TrialsTreatments Leslie Bradford, MD has experience with
- Olaparib
- Paclitaxel
- Bevacizumab
- Carboplatin
- Pembrolizumab
- Cediranib Maleate
Breakdown of trials Leslie Bradford, MD has run
Ovarian Cancer
Parotid Gland Cancer
Cervical Adenocarcinoma
Endometrial Cancer
Serous Cystadenocarcinoma
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