Dr. Kavitha Ramaswamy
Claim this profileMemorial Sloan Kettering Cancer Center
Studies Non-Hodgkin's Lymphoma
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14 reported clinical trials
44 drugs studied
Area of expertise
1Non-Hodgkin's Lymphoma
Philadelphia chromosome positive
CD22 positive
Stage I
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Philadelphia chromosome positive
CD22 positive
Stage I
Affiliated Hospitals
Clinical Trials Kavitha Ramaswamy is currently running
Inotuzumab Ozogamicin
for Acute Lymphoblastic Leukemia
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting2 awards Phase 3
Inotuzumab Ozogamicin
for Leukemia and Lymphoma
This phase II trial studies how well inotuzumab ozogamicin works in treating younger patients with B-lymphoblastic lymphoma or CD22 positive B acute lymphoblastic leukemia that has come back (relapsed) or does not respond to treatment (refractory). Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a toxic agent called ozogamicin. Inotuzumab attaches to CD22 positive cancer cells in a targeted way and delivers ozogamicin to kill them.
Recruiting1 award Phase 210 criteria
More about Kavitha Ramaswamy
Clinical Trial Related5 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Kavitha Ramaswamy has experience with
- Dexamethasone
- Cyclophosphamide
- Pegaspargase
- Prednisolone
- Mercaptopurine
- Methotrexate
Breakdown of trials Kavitha Ramaswamy has run
Non-Hodgkin's Lymphoma
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Lymphoma
T-Lymphoblastic Leukemia/Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Kavitha Ramaswamy specialize in?
Kavitha Ramaswamy focuses on Non-Hodgkin's Lymphoma and Relapse. In particular, much of their work with Non-Hodgkin's Lymphoma has involved Philadelphia chromosome positive patients, or patients who are CD22 positive.
Is Kavitha Ramaswamy currently recruiting for clinical trials?
Yes, Kavitha Ramaswamy is currently recruiting for 3 clinical trials in New York New York. If you're interested in participating, you should apply.
Are there any treatments that Kavitha Ramaswamy has studied deeply?
Yes, Kavitha Ramaswamy has studied treatments such as Dexamethasone, Cyclophosphamide, Pegaspargase.
What is the best way to schedule an appointment with Kavitha Ramaswamy?
Apply for one of the trials that Kavitha Ramaswamy is conducting.
What is the office address of Kavitha Ramaswamy?
The office of Kavitha Ramaswamy is located at: Memorial Sloan Kettering Cancer Center, New York, New York 10065 United States. This is the address for their practice at the Memorial Sloan Kettering Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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