Howard Gross, MD | Premier Health

Dr. Howard M. Gross

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Kettering Medical Center

Expert in Breast Cancer
Expert in Cancer
134 reported clinical trials
200 drugs studied

About Howard M. Gross

Education:

  • Obtained MD (Doctor of Medicine) from the University of Cincinnati College of Medicine in 1986.

Experience:

  • Board Certified in Internal Medicine by the American Board of Internal Medicine.
  • Has been practicing medicine since 1986, specializing in internal medicine.
  • Affiliated with Miami Valley Hospital North and other Dayton area medical facilities.

Area of expertise

1

Breast Cancer

Global Leader

Howard M. Gross has run 23 trials for Breast Cancer. Some of their research focus areas include:

HER2 positive
Stage IV
ER positive
2

Cancer

Global Leader

Howard M. Gross has run 21 trials for Cancer. Some of their research focus areas include:

Stage IV
KRAS positive
p16 positive

Affiliated Hospitals

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Kettering Medical Center

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Dayton Physician LLC-Miami Valley Hospital North

Clinical Trials Howard M. Gross is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

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Chemotherapy + Hormone Therapy

for Breast Cancer

This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.

Recruiting

2 awards

Phase 3

19 criteria

More about Howard M. Gross

Clinical Trial Related

7 years of experience running clinical trials · Led 134 trials as a Principal Investigator · 56 Active Clinical Trials

Treatments Howard M. Gross has experience with

  • Nivolumab
  • Pembrolizumab
  • Carboplatin
  • Paclitaxel
  • Cisplatin
  • Atezolizumab

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