Harriet Kluger, MD < Yale School of ...

Dr. Harriet Kluger, MD

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Yale Cancer Center

Studies Renal Cell Carcinoma
Studies Kidney Cancer
6 reported clinical trials
9 drugs studied

Area of expertise

1Renal Cell Carcinoma
Harriet Kluger, MD has run 4 trials for Renal Cell Carcinoma. Some of their research focus areas include:
Stage IV
Stage III
ALK positive
2Kidney Cancer
Harriet Kluger, MD has run 3 trials for Kidney Cancer. Some of their research focus areas include:
Stage IV
Stage III
ALK positive

Affiliated Hospitals

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Yale Cancer Center
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Yale-New Haven Hospital

Clinical Trials Harriet Kluger, MD is currently running

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ST-067-001

for Solid Tumors

This trial is testing a new drug called ST-067 on patients with certain types of cancer that have not responded to previous treatments. The goal is to find the safest and most effective dose and to see how well it works against these cancers.
Recruiting1 award Phase 1 & 22 criteria
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Etrasimod + Corticosteroids

for Colitis

This is a randomized, double-blind, placebo-controlled, two-arm phase 2 study of etrasimod plus corticosteroids versus placebo plus corticosteroids for the treatment of IMDC CTCAE v5.0 grade ≥ 2 due to ICI therapy alone (α-PD-(L)1 monotherapy or combined with another ICI, such as α-CTLA-4 or α-LAG-3) or ICI plus an oral tyrosine kinase inhibitor that in the opinion of the treating physician requires treatment with corticosteroid-based immunosuppression and does not require immediate secondary immune suppression, such as vedolizumab or infliximab (or equivalent). IMDC is one of the most common Immune Related Adverse Events (irAEs) from treatment with ICI. Current guidelines recommend steroid treatment for IMDC CTCAE grade ≥ 2, which requires temporary or permanent cessation of ICI therapy. Corticosteroids may interfere with the anti-tumor activity of ICIs and are therefore not co-administered. Strategies are needed to both reduce the dose and duration of corticosteroids needed for IMDC treatment and minimize the duration off ICI therapy before re-administering ICI (for those patients in whom it is deemed safe to rechallenge).
Recruiting0 awards Phase 25 criteria

More about Harriet Kluger, MD

Clinical Trial Related5 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Harriet Kluger, MD has experience with
  • APX005M
  • Nivolumab
  • Ipilimumab
  • Etrasimod
  • ST-067
  • Cabiralizumab

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