Dr. Deepak C. D'Souza, M.D.
Claim this profileBiological Studies Unit, VA Connecticut Healthcare System
Studies Substance Abuse
Studies Cannabis
8 reported clinical trials
11 drugs studied
Affiliated Hospitals
Clinical Trials Deepak C. D'Souza, M.D. is currently running
THC
for HIV
In this study, the investigators hypothesize that THC alters the immunogenome in a cell type-specific fashion and alters cytokine production via epigenetic regulatory mechanisms and that these alterations differ between HIV-infected and HIV-uninfected host genomes.
Recruiting1 award Phase 16 criteria
PET Imaging
for Various Conditions
The aim of the present study is to assess the availability of cannabinoid receptors (CB1R) in the human brain. CB1R are present in everyone's brain, regardless of whether or not someone has used cannabis. The investigators will image brain cannabinoid receptors using Positron Emission Tomography (PET) imaging and the radioligand OMAR, in healthy individuals and several conditions including 1) cannabis use disorders, 2) psychotic disorders, 3) prodrome of psychotic illness and 4) individuals with a family history of alcoholism, 5) Post-Traumatic Stress Disorder 6) Opioid Use Disorder using the PET imaging agent or radiotracer, \[11C\]OMAR. This will allow us to characterize the number and distribution of CB1R in these conditions. It is likely that the list of conditions will be expanded after the collection of pilot data and as new data on cannabinoids receptor function and psychiatric disorders becomes available. Those in the cannabis us disorder arm of the study will have a PET scan on at least three occasions: once while smoking as usual, once after 48-hours of abstinence from cannabis, and a final time after 4 weeks of abstinence. Additional scans may be conducted within the 4 weeks and the last scan may be conducted well beyond 4 weeks. Similarly, while most schizophrenia patients may get scanned just once, a subgroup of patients may get scanned more than once. For example to tease out the effects of medications, unmedicated patients may get scanned while unmedicated and again after treatment with antipsychotic medications. Similarly prodromes may get scanned while in the prodromal stage off medications, on medications and after conversion to schizophrenia.
Recruiting1 award N/A9 criteria
More about Deepak C. D'Souza, M.D.
Clinical Trial Related4 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Deepak C. D'Souza, M.D. has experience with
- Active Ethanol
- Placebo
- Iclepertin
- [11-C]OMAR
- PF-04457845
- Dimethyltryptamine (DMT)
Breakdown of trials Deepak C. D'Souza, M.D. has run
Substance Abuse
Cannabis
Hangover
Driving Under the Influence (DUI)
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Deepak C. D'Souza, M.D. specialize in?
Deepak C. D'Souza, M.D. focuses on Substance Abuse and Cannabis. In particular, much of their work with Substance Abuse has involved treating patients, or patients who are undergoing treatment.
Is Deepak C. D'Souza, M.D. currently recruiting for clinical trials?
Yes, Deepak C. D'Souza, M.D. is currently recruiting for 2 clinical trials in West Haven Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Deepak C. D'Souza, M.D. has studied deeply?
Yes, Deepak C. D'Souza, M.D. has studied treatments such as Active Ethanol, Placebo, Iclepertin.
What is the best way to schedule an appointment with Deepak C. D'Souza, M.D.?
Apply for one of the trials that Deepak C. D'Souza, M.D. is conducting.
What is the office address of Deepak C. D'Souza, M.D.?
The office of Deepak C. D'Souza, M.D. is located at: Biological Studies Unit, VA Connecticut Healthcare System, West Haven, Connecticut 06516 United States. This is the address for their practice at the Biological Studies Unit, VA Connecticut Healthcare System.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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