Dr. Joao P. De Aquino, M.D.
Claim this profileVA Healthcare System
Studies Chronic Persistent Surgical Pain
Studies Pain
4 reported clinical trials
4 drugs studied
Affiliated Hospitals
Clinical Trials Joao P. De Aquino, M.D. is currently running
Dronabinol
for Pain Management in Opioid Users
Twenty male and female (ages 18-70) participants with OUD currently receiving methadone or buprenorphine will be enrolled. Prior to their daily methadone or buprenorphine dose and thus at trough plasma levels of opioid, participants will receive dronabinol (2.5 mg, 5mg) or placebo. Subsequently, all participants will undergo laboratory testing of opioid-related outcomes. Pain sensitivity will be measured using a technique called the (QST) quantitative sensory testing, which involves the administering heat or cold stimulation. A Short-Form McGill Pain Questionnaire (SF-MPQ) and a pain Visual Analog Scale (VAS). Attentional bias will be measured using a visual probe task. Negative affect will be measured using the Positive and Negative Affect Schedule (PANAS). Cognitive performance will be measured by a comprehensive cognitive battery. The order of study medication administration will be counterbalanced order to minimize carryover effects. On the initial screening day and at the end of medication treatment, blood will be drawn to determine serum cytokine levels. One week after the last study medication dose, a follow-up session will be conducted during which participants will undergo urine toxicology testing and a safety evaluation before final discharge from the study.
Recruiting0 awards Phase < 1
THC
for Pain Relief in Older Adults
The overarching goal of this double-blind, placebo-controlled, crossover study is to characterize the pharmacokinetic (PK) and pharmacodynamic (PD) effects of the main analgesic and psychoactive constituent of cannabis, delta-9 tetrahydrocannabinol (THC), among older adults - the fastest growing population of cannabis consumers, and the most likely age cohort to use cannabinoids to relieve pain. This protocol includes two sub-studies, each randomizing 20 men and women aged 65 years or older to receive two administration routes of THC; oral administration and vaporized administration.
Recruiting0 awards Phase < 1
More about Joao P. De Aquino, M.D.
Clinical Trial Related6 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Joao P. De Aquino, M.D. has experience with
- Dronabinol
- Placebo
- Cannabidiol
- Purified THC In An Ethanolic Solution
Breakdown of trials Joao P. De Aquino, M.D. has run
Chronic Persistent Surgical Pain
Opioid Use Disorder
Opiate Dependence
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Joao P. De Aquino, M.D. specialize in?
Joao P. De Aquino, M.D. focuses on Chronic Persistent Surgical Pain and Pain. In particular, much of their work with Chronic Persistent Surgical Pain has involved treating patients, or patients who are undergoing treatment.
Is Joao P. De Aquino, M.D. currently recruiting for clinical trials?
Yes, Joao P. De Aquino, M.D. is currently recruiting for 3 clinical trials in West Haven Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Joao P. De Aquino, M.D. has studied deeply?
Yes, Joao P. De Aquino, M.D. has studied treatments such as Dronabinol, Placebo, Cannabidiol.
What is the best way to schedule an appointment with Joao P. De Aquino, M.D.?
Apply for one of the trials that Joao P. De Aquino, M.D. is conducting.
What is the office address of Joao P. De Aquino, M.D.?
The office of Joao P. De Aquino, M.D. is located at: VA Healthcare System, West Haven, Connecticut 06516 United States. This is the address for their practice at the VA Healthcare System.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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