Dr. Brian L Burnette, MD - Green Bay ...

Dr. Brian L. Burnette

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Saint Vincent Hospital Cancer Center Green Bay

Studies Breast Cancer
Studies Breast cancer
31 reported clinical trials
85 drugs studied

Area of expertise

1

Breast Cancer

Brian L. Burnette has run 8 trials for Breast Cancer. Some of their research focus areas include:

HER2 positive
Stage II
Stage III
2

Breast Cancer

Brian L. Burnette has run 7 trials for Breast cancer. Some of their research focus areas include:

HER2 positive
Stage II
Stage III

Affiliated Hospitals

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Saint Vincent Hospital Cancer Center Green Bay

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Saint Vincent Hospital Cancer Center At Saint Mary's

Clinical Trials Brian L. Burnette is currently running

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Pembrolizumab + Radiation vs Chemotherapy + Radiation

for Head and Neck Cancer

This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or patients with a second head and neck cancer that is not from metastasis (primary). Radiation therapy uses high energy radiation or protons to kill tumor cells and shrink tumors. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of cancer cells. Carboplatin is also in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of cancer cells. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab alone after surgery may work better than the usual approach in shrinking recurrent or primary head and neck squamous cell carcinoma.

Recruiting

1 award

Phase 2

31 criteria

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Venetoclax + HMA

for Acute Myeloid Leukemia

This phase II MyeloMATCH treatment trial compares the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib in treating older and unfit patients with acute myeloid leukemia and FLT3 mutations. Azacitidine is a drug that is absorbed into DNA and leads to the activation of cancer suppressor genes, which are genes that help control cell growth. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Gilteritinib is in a class of medications called kinase inhibitors. It works by blocking the action of a certain naturally occurring substance that may be needed to help cancer cells multiply. This study may help doctors find out if these different approaches are better than the usual approaches. To decide if they are better, the study doctors are looking to see if the study drugs lead to a higher percentage of patients achieving a deeper remission compared to the usual approach.

Recruiting

1 award

Phase 2

7 criteria

More about Brian L. Burnette

Clinical Trial Related

5 years of experience running clinical trials · Led 31 trials as a Principal Investigator · 13 Active Clinical Trials

Treatments Brian L. Burnette has experience with

  • Carboplatin
  • Nivolumab
  • Fluorouracil
  • Paclitaxel
  • Cisplatin
  • Pembrolizumab

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