Langevin, Anne-Marie R MD | Profiles

Dr. Anne-Marie R. Langevin

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University of Texas Health Science Center at San Antonio

Expert in Brain Tumor
Expert in Cancer
66 reported clinical trials
116 drugs studied

About Anne-Marie R. Langevin

Education:

  • Obtained MD from the University of Texas Health Science Center at San Antonio in 2008.
  • Completed Residency in Obstetrics and Gynecology at the same institution in 2012.
  • Finished Fellowship in Reproductive Endocrinology and Infertility in 2015 at the University of Texas Health Science Center at San Antonio.

Experience:

  • Currently serves as an Associate Professor in the Department of Obstetrics and Gynecology at the University of Texas Health Science Center at San Antonio.

Area of expertise

1Brain Tumor
Global Leader
Anne-Marie R. Langevin has run 21 trials for Brain Tumor. Some of their research focus areas include:
Stage I
Stage II
Stage IV
2Cancer
Global Leader
Anne-Marie R. Langevin has run 20 trials for Cancer. Some of their research focus areas include:
Stage I
Stage IV
Stage II

Affiliated Hospitals

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University Of Texas Health Science Center At San Antonio
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University Of Texas

Clinical Trials Anne-Marie R. Langevin is currently running

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Inotuzumab Ozogamicin

for Acute Lymphoblastic Leukemia

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting2 awards Phase 3
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Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3

More about Anne-Marie R. Langevin

Clinical Trial Related8 years of experience running clinical trials · Led 66 trials as a Principal Investigator · 24 Active Clinical Trials
Treatments Anne-Marie R. Langevin has experience with
  • Cyclophosphamide
  • Radiation Therapy
  • Etoposide
  • Vincristine Sulfate
  • Doxorubicin Hydrochloride
  • Vincristine

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